36402-80-9Relevant articles and documents
A Short synthesis of benzomorphane analgesics (±)-Metazocine and (±)-Phenazocine
Singh, Kamal Nain,Singh, Pushpinder,Sharma, Arvind Kumar,Singh, Paramjit,Kessar, Satinder V.
experimental part, p. 3716 - 3720 (2010/12/29)
A three step synthesis of (±)-metazocine and (±)-phenazocine starting with 3,4-lutidine is described. The key step involves Lewis acid promoted lithiation/electrophilic substitution reaction of N-alkyl-3,4-dimethyl- 1,2,5,6- tetrahydropyridine. Copyright
Enantiopure n-acyldihydropyridones as synthetic intermediates: Asymmetric synthesis of benzomorphans
Comins, Daniel L.,Zhang, Yue-Mei,Joseph, Sajan P.
, p. 657 - 659 (2008/02/12)
(Matrix presented) Concise asymmetric syntheses of several benzomorphan derivatives have been accomplished using enantiopure 2,3-dihydro-4-pyridones as chiral building blocks.
An improved resolution of (±)-cis-N-normetazocine
Brine,Berrang,Hayes,Carroll
, p. 2139 - 2143 (2007/10/02)
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