244263-92-1

Upstream product

• 244263-89-6 N⁶-benzoyl-9-[6,7-dideoxy-2,3-O-isopropylidene-7-C-(trimethylsilyl)-β-D-allo-hept-6-ynofuranosyl]adenine 

Downstream Products

• 847205-42-9 C₆₅H₈₈N₁₀O₁₀Si₃ 
• 847205-39-4 N⁶-benzoyl-2',3'-O-isopropylidene-5'-O-(triethylsilyl)adenosin-8-yl-(8->7'-C)-N⁶-benzoyl-9-[6,7-dideoxy-2,3-O-isopropylidene-β-D-allo-hept-6-ynofuranosyl]adenine 
• 323203-87-8 N⁶-benzoyl-9-[6,7-dideoxy-2,3-O-isopropylidene-5-O-(triethylsilyl)-β-D-allo-hept-6-ynofuranosyl]adenine 
• 847205-26-9 N⁶-benzoyl-9-[6,7-dideoxy-2,3-O-isopropylidene-5-O-(triisopropylsilyl)-β-D-allo-hept-6-ynofuranosyl]adenine 

Relevant academic research and scientific papers

Oligonucleosides with a nucleobase-including backbone: Part 12 - Synthesis of mixed ethynylene-linked uridine- and adenosine-derived tetramers

In contradistinction to the corresponding Grignard reagent, bis[(trimethylsilyl)ethynyl]zinc reacted with the 5′-oxoadenosine 3 diastereoselectively to the β-D-allo-hept-6-ynofuranosyladenine 5. Lithiation/iodination of the monomeric propargyl alcohol 5 a

Oligonucleosides with a nucleobase-including backbone. Part 3. Synthesis of acetyleno-linked adenosine dimers

The adenosine-derived dimers 14a-d and 15b-d have been prepared by coupling the protected 8-iodoadenosines 3 and 13 with the C(5′)-ethynylated adenosine derivatives 5, 6, 11, and 12 (Scheme 4). Similarly, the 5′-epimeric dimer 16 was prepared by coupling