24445-06-5Relevant articles and documents
Functionalization of 4,5-dihydrobenzo[g]indazoles using magnesium- or zinc-heterocyclic intermediates
Despotopoulou, Christina,Gignoux, Camille,McConnell, Darryl,Knochel, Paul
experimental part, p. 3661 - 3671 (2010/03/03)
4,5-Dihydrobenzo[g]indazoles were efficiently metallated using hindered Mg- and Zn-TMP amides. Trapping of the resulting organometallic reagents with various electrophiles furnished novel C3-substituted 4,5-dihydrobenzo[g] indazoles.
Synthesis and Study of the Potential Antiallergic Activity of Some Pyrazole Derivatives
Parsia, Maria T. Di,Suarez, Cecilia,Vitolo, Maria J.,Marquez, Victor E.,Beyer, Bernardo,et al.
, p. 117 - 119 (2007/10/02)
The synthesis and study of the oral antiallergic activity of a series of monopyrazole derivatives (2-14) considered as analogues of active bispyrazole 1 are described.None of the compounds showed significant inhibition of the rat passive cutaneous anaphylaxis (PCA), with the exception of the already known 5-aminoindazole (2).The activity of this compound is, however, lower than that of compound 1.