24451-19-2

Upstream product

• 90-41-5 2-phenylaniline 
• 4755-77-5 Ethyl oxalyl chloride 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 42509-22-8 ethyl phenanthridine-6-carboxylate 
• 22548-80-7 N-Biphenyl-2-yl-N'-(2-octyloxy-phenyl)-oxalamide 
• 22548-81-8 N-Biphenyl-2-yl-N'-[2-(3-chloro-propoxy)-phenyl]-oxalamide 
• 22626-58-0 N-Biphenyl-2-yl-N'-(2-methoxy-phenyl)-oxalamide 
• 22486-42-6 N-([1,1‘-biphenyl-2-yl])-N‘-(2-hydroxyphenyl)-oxalamide 

Relevant academic research and scientific papers

Molybdenum and Tungsten Alkylidyne Complexes Containing Mono-, Bi-, and Tridentate N-Heterocyclic Carbenes

New tungsten and molybdenum alkylidyne complexes bearing mono-, bi-, and tridentate N-heterocyclic carbenes (NHCs) have been synthesized. Formation of unprecedented structures in complexes bearing N-tert-butyl substituents on the imidazol(in)-2-ylidene was observed, leading to molybdenum complexes containing an abnormal carbene (Mo-4) and a bridging O,C,C-pincer ligand (Mo-10) and to a tungsten complex containing a cationic imidazolinium-tagged alkoxide forming an inner salt with an anionic tungsten center (W-5). Both the abnormal carbene binding in Mo-4 and the O,C,C-pincer-type structure of Mo-10 were confirmed by single-crystal X-ray analysis, and the proposed structure of W-5 is supported by the single-crystal X-ray structure of a minor byproduct (W-8) formed during the synthesis of W-4, displaying the aforementioned inner-salt-like structure. The novel alkylidyne complexes were also investigated for their capability to form a previously postulated quasi-cationic species with a weakly coordinating anion (WCA) during the alkyne homometathesis of 1-phenyl-1-propyne. Overall, incorporation of bidentate and strongly σ donating NHCs as well as introduction of better leaving groups did not lead to the expected increase in catalytic activity. Despite identical ligand spheres, changing from molybdenum to tungsten led to complete loss of activity in the bidentate systems.

Efficient copper-catalyzed amination of DNA-conjugated aryl iodides under mild aqueous conditions

Herein, we describe the development of copper-catalyzed cross-coupling of DNA-conjugated aryl iodides with aliphatic amines. This protocol leverages a novel ligand, 2-((2,6-dimethoxyphenyl)amino)-2-oxoacetic acid, to effect the transformation in aqueous D

METHOD FOR PRODUCING BENZAZEPINONE

It is an object of the present invention to provide 2-iminocarboxylic acid derivatives, and a practically suitable industrial method for producing benzazepinones in a short process under mild conditions. The present invention provides a method for producing a benzazepinone or a salt thereof, which comprises opening a ring of an isoquinoline derivative and subsequently converting the thus generated amine into a benzazepinone through lactamization reaction.