244638-67-3Relevant academic research and scientific papers
Pyrazolopyridinones as functionally selective GABAA ligands
Blackaby, Wesley P.,Atack, John R.,Bromidge, Frances,Lewis, Richard,Russell, Michael G.N.,Smith, Alison,Wafford, Keith,McKernan, Ruth M.,Street, Leslie J.,Castro, Jose L.
, p. 4998 - 5002 (2007/10/03)
2,5-Dihydro-3H-pyrazolo[4,3-c]pyridin-3-ones are GABAA receptor benzodiazepine binding site ligands, which can exhibit functional selectivity for the α3 subtype over the α1 subtype. SAR studies to optimize this functional
