24464-39-9 Usage
General Description
6-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE is a chemical compound that belongs to the class of tetrahydroisoquinolines. It is commonly used in the field of medicinal chemistry for the development of potential pharmaceutical drugs due to its various biological activities, including anti-inflammatory and analgesic properties. 6-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE has also been studied for its potential use in the treatment of neurodegenerative diseases, such as Parkinson's and Alzheimer's, as well as for its antitumor and antiviral activities. The synthesis and biological evaluation of 6-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE derivatives continue to be areas of interest in the research community.
Check Digit Verification of cas no
The CAS Registry Mumber 24464-39-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,4,6 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 24464-39:
(7*2)+(6*4)+(5*4)+(4*6)+(3*4)+(2*3)+(1*9)=109
109 % 10 = 9
So 24464-39-9 is a valid CAS Registry Number.
24464-39-9Relevant articles and documents
Regioexhaustive Functionalization of the Carbocyclic Core of Isoquinoline: Concise Synthesis of Oxoaporphine Core and Ellipticine
Horváth, Dániel Vajk,Domonyi, Frigyes,Palkó, Roberta,Lomoschitz, Andrea,Soós, Tibor
, p. 2181 - 2190 (2018/03/21)
A general and versatile strategy has been developed for the functionalization of the carbocyclic core of the isoquinoline. This regioexhaustive approach employs electrophilic halogenation as a toolbox methodology and delivers highly decorated intermediates that can be further elaborated toward medicinally relevant building blocks or natural products.
Ready access to 6-alkyl, 6-phenyl, 5,6-dialkyl, and 5-alkyl-6-phenyl substituted 1,2,3,4-tetrahydroisoquinolines
Nussbaumer,Dechat
, p. 1047 - 1055 (2007/10/03)
Readily available bicyclic enone precursors were used in a novel strategy for the synthesis of 6-mono- and 5,6-disubstituted tetrahydroisoquinolines (alkyl and phenyl in position 6, hydrogen and methyl in position 5). After 1,2-addition of the respective
