2447-93-0

Basic information

• Product Name: 2-Chloro-N-(4-Methylphenyl)benzaMide, 97%
• Synonyms: 2-Chloro-N-(4-Methylphenyl)benzaMide, 97%
• CAS NO: 2447-93-0
• Molecular Formula: C₁₄H₁₂ClNO
• Molecular Weight: 245.70418
• Mol File: 2447-93-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 305.6°Cat760mmHg
• Flash Point: 138.6°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 0.000816mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 2-Chloro-N-(4-Methylphenyl)benzaMide, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-N-(4-Methylphenyl)benzaMide, 97%(2447-93-0)
• EPA Substance Registry System: 2-Chloro-N-(4-Methylphenyl)benzaMide, 97%(2447-93-0)

Safety Data

• Hazardous Substances Data: 2447-93-0(Hazardous Substances Data)

Usage

General Description

2-Chloro-N-(4-Methylphenyl)benzamide, 97% is an organic compound that is commonly used in research and chemical synthesis. It is a white to off-white crystalline powder with a high purity of 97%. 2-Chloro-N-(4-Methylphenyl)benzaMide, 97% is used in the pharmaceutical industry for the production of various medications and is also used in the synthesis of other organic compounds. It is important to handle this chemical with care and follow proper safety protocols while working with it in a laboratory setting.

InChI:InChI=1/C14H12ClNO/c1-10-6-8-11(9-7-10)16-14(17)12-4-2-3-5-13(12)15/h2-9H,1H3,(H,16,17)

Upstream product

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Downstream Products

• 14959-73-0 3,4-diphenyl-2-(p-tolyl)isoquinolin-1(2H)-one 
• 66087-54-5 2-Chlor-N,4'-dimethylbenzanilid 
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• 33238-15-2 3-phenylmethylene-2-(4-methylphenyl)isoindole-1-one 
• 1384754-96-4 [(C₆H₄C(O)NC₆H₄-4-Me)Co(III)(Cl-ortho-C₆H₄C(O)NC₆H₄-4-Me)(trimethylphosphine)2] 
• 1384754-93-1 trans-[(C₆H₄C(O)NHC₆H₄-4-Me)Ni(II)(trimethylphosphine)2Cl] 
• 14959-59-2 C₂₈H₂₁NO 
• 213454-64-9 ethyl ethyl-1,4-dihydro-2-methyl-4-(4'-methylphenyl)imino-3-quinolinecarboxylate 
• 213454-29-6 N-(α,o-dichlorobenzylidene)aniline 

Relevant articles and documents

Catalyst-Free Singlet Oxygen-Promoted Decarboxylative Amidation of α-Keto Acids with Free Amines

A novel catalyst-free decarboxylative amidation of α-keto acids with amines under mild conditions has been developed. Advantages of the new protocol include avoidance of metal catalysts and high levels of functional group tolerance. In addition, the reaction can be scaled up and shows high chemoselectivity. Preliminary mechanistic studies suggest that singlet oxygen, generated from oxygen under irradiation, is the key promoter for this catalyst-free transformation.

Efficient and convenient deprotection of thiocarbonyl to carbonyl compounds using 3-carboxypyridinium and 2,2′-bipyridinium chlorochromates in solution, dry media, and under microwave irradiation

A synthetic utility of 3-carboxypyridinium (CPCC) and 2,2′- bipyridinium (BPCC) chlorochromates in deprotection reactions is reported. Different types of thioamides, thioureas, thiono esters, and thioketones are deprotected to their corresponding carbonyl compounds with these reagents in good to excellent yields. The reactions were carried out in solution, under solvent-free conditions, and under microwave irradiation. The results show that with both reagents the rates of the reactions and the yields are usually highest under microwave irradiation. Springer-Verlag 2003.

Selective conversion of thioamides and thioureas to their oxygen analogues using quinolinium fluorochromate

The synthetic utility of quinolinium fluorochromate (QFC) in deprotection of thiocarbonyl compounds is reported. A variety of primary and secondary thioamides and thioureas are converted to their oxo derivatives in high yields. However, tertiary thioamides afford their amides in relatively poor yields. Selective deprotection of thioamides and thioureas in the presence of thionoesters and thioketones is noteworthy advantage of this method.