244755-79-1

Basic information

• Product Name: 1H-Naphth[2,3-f]isoindole-1,3(2H)-dione, 2-[(1R,2R)-2-hydroxycyclohexyl]-
• CAS NO: 244755-79-1
• Molecular Formula: C22H19NO3
• Molecular Weight: 345.398
• Mol File: 244755-79-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Naphth[2,3-f]isoindole-1,3(2H)-dione, 2-[(1R,2R)-2-hydroxycyclohexyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Naphth[2,3-f]isoindole-1,3(2H)-dione, 2-[(1R,2R)-2-hydroxycyclohexyl]-(244755-79-1)
• EPA Substance Registry System: 1H-Naphth[2,3-f]isoindole-1,3(2H)-dione, 2-[(1R,2R)-2-hydroxycyclohexyl]-(244755-79-1)

Safety Data

• Hazardous Substances Data: 244755-79-1(Hazardous Substances Data)

Upstream product

• 6812-14-2 2,3-anthracenedicarboxylic acid anhydride 
• 931-15-7 (1R,2R)-2-aminocyclohexanol 
• 5456-63-3 trans-2-aminocyclohexanol hydrochloride 
• 22204-53-1 (2S)-2-(6-methoxy(2-naphthyl))propanoic acid 

Downstream Products

• 1262552-76-0 C₃₄H₄₁NO₄ 
• 1262552-77-1 C₃₄H₄₁NO₄ 
• 1262552-78-2 C₃₄H₄₁NO₄ 
• 1262552-79-3 C₃₄H₄₁NO₄ 

Relevant articles and documents

Studies on tridecaptin B1, a lipopeptide with activity against multidrug resistant Gram-negative bacteria

Previously other groups had reported that Paenibacillus polymyxa NRRL B-30507 produces SRCAM 37, a type IIA bacteriocin with antimicrobial activity against Campylobacter jejuni. Genome sequencing and isolation of antimicrobial compounds from this P. polymyxa strain show that the antimicrobial activity is due to polymyxins and tridecaptin B1. The complete structural assignment, synthesis, and antimicrobial profile of tridecaptin B1 is reported, as well as the putative gene cluster responsible for its biosynthesis. This peptide displays strong activity against multidrug resistant Gram-negative bacteria, a finding that is timely to the current problem of antibiotic resistance.