244768-98-7

Basic information

• Product Name: tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate
• Synonyms: tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate;(1S,4S)-5-Methyl-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester;tert-butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carbo×ylate;2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid, 5-methyl-, 1,1-dimethylethyl ester, (1S,4S)-
• CAS NO: 244768-98-7
• Molecular Formula: C11H20N2O2
• Molecular Weight: 212.2887
• Mol File: 244768-98-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 272℃
• Flash Point: 118℃
• Appearance: /
• Density: 1.091
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate(244768-98-7)
• EPA Substance Registry System: tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate(244768-98-7)

Safety Data

• Hazardous Substances Data: 244768-98-7(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate is a chemical compound that is commonly known as a tert-butyl ester. It is used in the pharmaceutical industry as a building block for the synthesis of various drug molecules. tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate has a bicyclic structure, which makes it valuable for medicinal chemistry research as it can potentially enhance the biological activity of pharmaceutical compounds. The tert-butyl group in the compound provides stability and protection to the carboxylate functional group, allowing for better control over chemical reactions. Overall, tert-Butyl 5-Methyl-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate plays a crucial role in the development of new pharmaceuticals and chemical compounds.

Upstream product

• 50-00-0 formaldehyd 
• 113451-59-5 (1S,4S)-2,5-Diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 
• 74-88-4 methyl iodide 
• 61478-27-1 (2S,4S)-N-(tert-butoxycarbonyl)-4-(p-toluenesulfonyloxy)-2-<(p-toluenesulfonyloxy)methyl>pyrrolidine 
• 74-89-5 methylamine 

Downstream Products

• 52321-26-3 (1S,4S)-5-methyl-2,5-diazabicyclo<2.2.1>heptane dihydrochloride 

Relevant articles and documents

Inhibitors of Bruton's Tyrosine Kinase

This application discloses 6-(2-Hydroxymethyl-phenyl)-2-methyl-2H-pyridazin-3-one derivatives according to generic Formula I: wherein, variables X, R, and Y4, are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation, such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient.

SUBSTITUTED BICYCLIC PIPERIDINYL-AND PIPERAZINYL- SULFONAMIDES USEFUL TO INHIBIT 11β-HYDROXYSTEROID DEHYDROGENASE TYPE-1

In its many embodiments, the present invention relates to a novel class of substituted bicyclic piperidinyl- and piperazinylsulfonamide compounds useful to inhibit 11β-hydroxysteroid dehydrogenase type-I, pharmaceutical compositions containing the compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the expression of 11β-hydroxysteroid dehydrogenase type-I using such compounds or pharmaceutical compositions.