24486-75-7Relevant articles and documents
Acylation of Heterocycles with Carbonic Acid Derivatives. II. Endo and Exo Carbamoylation of 2-Amino-benzimidazole Derivatives with Isocyanates. Mechanism of the Acyl Group Migration
Graubaum, Heinz,Martin, Dieter,Szeibert, Dagmar,Breckner, Michael,Glatt, Hans Horst,et. al.
, p. 809 - 815 (2007/10/02)
2-Amino-benzimidazoles react with isocyanates with good yields to give 2-amino-1-carbamoyl-aminobenzimidazoles 1 at -30 deg C and the corresponding 2-carbamoyl isomeres 2 at room temperature, respectively.The isomerization mechanism was studied by crossov