245068-66-0

Upstream product

• 50866-82-5 2,3:4,5-di-O-isopropylidene-aldehydo-D-ribose 
• 4762-26-9 hexyltriphenylphosphonium bromide 
• 252188-63-9 (4R,5S)-5-Heptyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 220125-71-3 [(4S,5S)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 

Downstream Products

• 128318-02-5 (2S,3S)-1-tosyloxy-2,3-decanediol 
• 209479-94-7 (3R,9R,10R)-10-tert-butyldimethylsilyloxy-3-tert-butyldiphenylsilyloxy-heptadec-1-ene-4,6-diyne-9-ol 
• 87005-03-6 (3R,9R,10R)-panaxytriol 
• 124901-75-3 (2R,3R)-1-tosyloxy-2,3-decanediol 

Relevant academic research and scientific papers

Synthesis of a new type of antitumour agent panaxytriol: Synthesis of its four diastereomers

Synthesis of four diastereomers of panaxytriol has been described. The basic objective is to create two acetylenic precursors followed by cuprous chloride mediated C-C bond coupling reaction.

Syntheses of two diastereoisomers of panaxytriol, a potent antitumor agent isolated from Panax ginseng

(3R, 9R, 10R) and (3R, 9S, 10S) diastereoisomers (2 and 3) of panaxytriol (1) were synthesized, and the absolute configuration of panaxytriol was confirmed as (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10- triol.