124901-75-3

Upstream product

• 74867-37-1 (2R,3R)-1,2,3-Trihydroxydecane 
• 98-59-9 p-toluenesulfonyl chloride 
• 124901-76-4 [(4R,5R)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methyl-1-benzenesulfonate 
• 245068-66-0 [(4S,5S)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methyl-1-benzenesulfonate 
• 130967-61-2 [(4R,5R)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 
• 252188-58-2 (4S,5R)-5-Heptyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 4762-26-9 hexyltriphenylphosphonium bromide 
• 220125-71-3 [(4S,5S)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 
• 123932-68-3 (2R,3S)-3-heptyloxirane methanol 
• 209479-89-0 (4R,5S,4'R)-5-((Z)-Hept-1-enyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl] 
• 209479-90-3 (4R,5S,4'R)-5-Heptyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl] 
• 21369-64-2 n-hexyllithium 

Downstream Products

• 124901-76-4 [(4R,5R)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 4-methyl-1-benzenesulfonate 
• 130258-88-7 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-1-ethyl-6-((4R,5R)-5-heptyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-hexa-2,4-diynyl ester 
• 130258-88-7 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-1-ethyl-6-((4R,5R)-5-heptyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-hexa-2,4-diynyl ester 
• 209479-94-7 (3R,9R,10R)-10-tert-butyldimethylsilyloxy-3-tert-butyldiphenylsilyloxy-heptadec-1-ene-4,6-diyne-9-ol 
• 87005-03-6 (3R,9R,10R)-panaxytriol 

Relevant academic research and scientific papers

Synthesis of panaxytriol and its stereoisomers as potential antitumor drugs

An efficient synthesis of panaxytriol and its seven stereoisomers was achieved, and four unnatural diastereomers of 2a were prepared. The key steps involved the opening of vicinal hydroxy epoxides, the stereospecific opening of the epoxides with perchlori

Synthesis of a new type of antitumour agent panaxytriol: Synthesis of its four diastereomers

Synthesis of four diastereomers of panaxytriol has been described. The basic objective is to create two acetylenic precursors followed by cuprous chloride mediated C-C bond coupling reaction.

Syntheses of two diastereoisomers of panaxytriol, a potent antitumor agent isolated from Panax ginseng

(3R, 9R, 10R) and (3R, 9S, 10S) diastereoisomers (2 and 3) of panaxytriol (1) were synthesized, and the absolute configuration of panaxytriol was confirmed as (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10- triol.

First total synthesis of panaxytriol, a potent antitumor agent isolated from Panax ginseng

Panaxytriol 1, a potent antitumor agent isolated from Panax ginseng, was first synthesized, and its stereostructure was confirmed to be (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10-triol.

Synthesis and the Absolute Configuration of Panaxacol

Panaxacol, a polyacetylene isolated from the callus of Panax ginseng, was synthesized from D-(-)-diethyl tartrate.The absolute configuration of panaxacol was determined to be 9R,10R.