245078-06-2Relevant articles and documents
5'-Phosphoramidates and 5'-diphosphates of 2'-O-allyl-β-D- arabinofuranosyl-uracil, -cytosine, and -adenine: Inhibition of ribonucleotide reductase
Manfredini, Stefano,Baraldi, Pier Giovanni,Durini, Elisa,Vertuani, Silvia,Balzarini, Jan,De Clercq, Erik,Karlsson, Anna,Buzzoni, Valentina,Thelander, Lars
, p. 3243 - 3250 (2007/10/03)
Continuing our studies on ribonucleotide reductase (RNR) mechanism-based inhibitors, we have now prepared the diphosphates (DP) of 2'-O-allyl-1-β-D- arabinofuranosyl-uracil and -cytosine and 2'-O-allyl-9-β-D-arabinofuranosyl- adenine and evaluated their i