Welcome to LookChem.com Sign In|Join Free

CAS

  • or

157024-75-4

Post Buying Request

157024-75-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 2,4(1H,3H)-Pyrimidinedione, 1-[3,5-bis-O-(tetrahydro-2H-pyran-2-yl)-b-D-arabinofuranosyl]- Manufacturer/High quality/Best price/In stock

    Cas No: 157024-75-4

  • USD $ 3.0-3.0 / Kilogram

  • 1 Kilogram

  • 1-100 Metric Ton/Month

  • Dayang Chem (Hangzhou) Co.,Ltd.
  • Contact Supplier

157024-75-4 Usage

General Description

1-(3,5-Bis-O-(tetrahydro-2H-pyran-2-yl)-beta-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione is a complex chemical compound with a long and intricate name. It is a pyrimidine nucleoside analog, which means it is a molecule similar to the building blocks of nucleic acids like DNA and RNA. The compound contains a pyrimidine base (2,4(1H,3H)-pyrimidinedione) attached to a sugar molecule (beta-D-arabinofuranosyl) with two tetrahydro-2H-pyran-2-yl groups. 1-(3,5-BIS-O-(TETRAHYDRO-2H-PYRAN-2-YL)-BETA-D-ARABINOFURANOSYL)-2,4(1H,3H)-PYRIMIDINEDIONE has potential applications in medicinal chemistry and drug development, particularly as an antiviral or antitumor agent, due to its ability to interfere with nucleic acid synthesis and replication. However, its complex structure and potential side effects make it a challenging molecule to work with and further research is likely needed to fully understand its properties and potential uses.

Check Digit Verification of cas no

The CAS Registry Mumber 157024-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,0,2 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 157024-75:
(8*1)+(7*5)+(6*7)+(5*0)+(4*2)+(3*4)+(2*7)+(1*5)=124
124 % 10 = 4
So 157024-75-4 is a valid CAS Registry Number.

157024-75-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-hydroxy-3,5-di(O-tetrahydropyran-2-yl)β-D-arabinofuranosyl)uracil

1.2 Other means of identification

Product number -
Other names 9-(3,5-di-O-(tetrahydropyran-2-yl)-β-D-arabinofuranosyl)uracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:157024-75-4 SDS

157024-75-4Relevant articles and documents

SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 2'-O-ALLYL-1-beta-D-ARABINOFURANOSYL-URACIL, -CYTOSINE AND -ADENINE

Manfredini, Stefano,Baraldi, Pier Giovanni,Bazzanini, Rita,Simoni, Daniele,Balzarini, Jan,Clercq, Erik De

, p. 473 - 478 (1997)

-

3-methyl uridine and 4-methyl cytidine nucleoside compound, synthetic method and its pharmaceutical use

-

Paragraph 0021; 0036, (2016/10/08)

The invention discloses a 3-methyluridine and 4-methylcytidine nucleosides compound and a synthesis method and pharmaceutical application thereof, belonging to the field of medicinal chemistry. The compound has a structural formula as shown in the specification. The compound has the effects of simultaneously modifying sugar rings and basic groups, increasing the activity of the compound and reducing the toxicity, provides a good application prospect for development of like medicines and can be applied to preparation of anti-HBV (Hepatitis B virus) medicines. The synthesis method is simple and feasible and provides conditions for mass synthesis of the compound.

Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors

Manfredini, Stefano,Baraldi, Pier G.,Durini, Elisa,Porcu, Luca,Angusti, Angela,Vertuani, Silvia,Solaroli, Nicola,De Clercq, Erik,Karlsson, Anna,Balzarini, Jan

, p. 1329 - 1332 (2007/10/03)

Highly selective arabinofuranosyl nucleosides, which inhibit the mitochondrial thymidine kinase (TK-2) without affecting the closely related herpes simplex virus type 1 thymidine kinase (HSV-1 TK), varicella-zoster virus thymidine kinase (VZV-TK), cytosolic thymidine kinase (TK-1) or the multifunctional Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK), have been obtained. SAR studies indicate a close relation between the length of the substituent at the 2′ position of the arabinofuranosyl moiety and the inhibitory activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 157024-75-4