245107-60-2

Basic information

• Product Name: (2R,4R)-2-tert-Butyl-4-(2-methyl-allyl)-4-(2-methylsulfanyl-ethyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester
• CAS NO: 245107-60-2
• Molecular Weight: 405.558
• Mol File: 245107-60-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4R)-2-tert-Butyl-4-(2-methyl-allyl)-4-(2-methylsulfanyl-ethyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-2-tert-Butyl-4-(2-methyl-allyl)-4-(2-methylsulfanyl-ethyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester(245107-60-2)
• EPA Substance Registry System: (2R,4R)-2-tert-Butyl-4-(2-methyl-allyl)-4-(2-methylsulfanyl-ethyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester(245107-60-2)

Safety Data

• Hazardous Substances Data: 245107-60-2(Hazardous Substances Data)

Upstream product

• 1458-98-6 2-methyl-3-bromo-1-propene 
• 245107-59-9 benzyl (2R,4R)-2-tert-butyl-4-[2-(methylthio)ethyl]-5-oxo-1,3-oxazolidine-3-carboxylate 
• 630-19-3 pivalaldehyde 
• 1152-62-1 (2R)-2-[[(benzyloxy)carbonyl]amino]-4-(methylsulfanyl)butanoic acid 

Downstream Products

• 245107-61-3 (R)-2-Benzyloxycarbonylamino-4-methyl-2-(2-methylsulfanyl-ethyl)-pent-4-enoic acid 

Relevant articles and documents

Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K

The structure-based design and synthesis of lactam-constrained azapeptide inhibitors of human cathepsin K are described. Enhanced stability to proteolytic cleavage over acyclic analogues is discussed.