245125-89-7

Basic information

• Product Name: (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid benzyl ester
• Synonyms: (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid benzyl ester
• CAS NO: 245125-89-7
• Molecular Weight: 307.39
• Mol File: 245125-89-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid benzyl ester(245125-89-7)
• EPA Substance Registry System: (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid benzyl ester(245125-89-7)

Safety Data

• Hazardous Substances Data: 245125-89-7(Hazardous Substances Data)

Upstream product

• 245125-88-6 (2S,2'R)-benzyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}-2'-methylpropinoyl)oxy]-4-methylpentanoate 

Downstream Products

• 245125-92-2 tert-butyl (5S,6R)-5-[(2S)-2-[(2R)-3-[(2R)-2-tert-butoxycarbonylamino-3-(4-methoxyphenyl)-propionylamino]-2-methylpropionyloxy]-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2(E),7(E)-dienoate 
• 179093-49-3 (S)-2-{(R)-3-[(R)-2-tert-Butoxycarbonylamino-3-(4-methoxy-phenyl)-propionylamino]-2-methyl-propionyloxy}-4-methyl-pentanoic acid 
• 182486-25-5 tert-butyl (5S,6R)-5-[(2S)-2-[(2R)-3-[(2R)-2-tert-butoxycarbonylamino-3-(3-chloro-4-methoxyphenyl)propionylamino]-2-methylpropionyloxy]-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2(E),7(E)-dienoate 
• 179093-50-6 (S)-2-{(R)-3-[(R)-2-tert-Butoxycarbonylamino-3-(3-chloro-4-methoxy-phenyl)-propionylamino]-2-methyl-propionyloxy}-4-methyl-pentanoic acid 
• 124689-65-2 cryptophycin-1 
• 124689-64-1 cryptophycin C 
• 155645-51-5 Cryptophycin 4 
• 196794-47-5 benzyl (2S)-2-[(2R)-3-[(2R)-2-tert-butoxycarbonylamino-3-(3-chloro-4-methoxyphenyl) propionylamino]-2-methylpropionyloxy]-4-methylpentanoate 
• 245125-90-0 benzyl (2S)-2-[(2R)-3-[(2R)-2-tert-butoxycarbonylamino-3-(4-methoxyphenyl)propionylamino]-2-methylpropionyloxy]-4-methylpentanoate 

Relevant articles and documents

Total Synthesis of Cryptophycins-1, -3, -4, -24 (Arenastatin A), and -29, Cytotoxic Depsipeptides from Cyanobacteria of the Nostocaceae

A convergent synthesis of cryptophycins has been developed in which (5S,6R)-5-hydroxy-6-methyl-8-phenylocta-2(E),7(E)-dienoic acid (A) is coupled with an amino acid segment (B). Two stereo-selective routes to A are described, the first employing allylatio