245323-45-9 Usage
Description
Cbz-L-beta-hoMovaline, also known as a Cbz-protected derivative of L-homovaline, is a chemical compound used in organic synthesis. It is commonly used as a building block in the preparation of peptides and peptidomimetics, which are important in drug discovery and development. Cbz-L-beta-hoMovaline is a key intermediate in the synthesis of various pharmaceutical compounds, particularly in the development of peptide-based drugs. Its Cbz-protected form provides stability and ease of manipulation during synthesis, making it a valuable tool in the production of biologically active compounds. Additionally, the presence of the L-homovaline moiety in the compound can impart specific pharmacological properties to the final products derived from it.
Uses
Used in Pharmaceutical Industry:
Cbz-L-beta-hoMovaline is used as a building block for the synthesis of peptides and peptidomimetics for drug discovery and development. Its Cbz-protected form provides stability and ease of manipulation during synthesis, making it a valuable tool in the production of biologically active compounds.
Used in Peptide-based Drug Development:
Cbz-L-beta-hoMovaline is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly in the development of peptide-based drugs. The presence of the L-homovaline moiety in the compound can impart specific pharmacological properties to the final products derived from it.
Check Digit Verification of cas no
The CAS Registry Mumber 245323-45-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,5,3,2 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 245323-45:
(8*2)+(7*4)+(6*5)+(5*3)+(4*2)+(3*3)+(2*4)+(1*5)=119
119 % 10 = 9
So 245323-45-9 is a valid CAS Registry Number.
245323-45-9Relevant articles and documents
Organocatalytic asymmetric mannich reactions with JV-Boc and JV-Cbz protected α-amido sulfones (Boc: Tert-butoxycarbonyl, Cbz: Benzyloxycarbonyl)
Marianacci, Olindo,Micheletti, Gabriele,Bernardi, Luca,Fini, Francesco,Fochi, Mariafrancesca,Pettersen, Daniel,Sgarzani, Valentina,Ricci, Alfredo
, p. 8338 - 8351 (2008/04/01)
Different malonates and βketoesters can react with N-tert-butoxycarbonyl- (N-Boc) and N-benzyloxycarbonyl- (N-Cbz) protected α-amido sulfones in an organocatalytic asymmetric Mannich-type reaction. The reaction makes use of a simple and easily obtained ph
Synthesis of optically active β-amino acid N-carboxyanhydrides
Cheng, Jianjun,Ziller, Joseph W.,Deming, Timothy J.
, p. 1943 - 1946 (2007/10/03)
(Equation presented) Methodology has been developed for the general synthesis of optically active β-amino acid N-carboxyanhydrides (β-NCAs) through cyclization of Nβ-Boc or Nβ-Cbz β-amino acids using phosphorus tribromide. The format
