245328-53-4

Basic information

• Product Name: Benzoic acid, 2-[(2E)-1-oxo-3-phenyl-2-propenyl]-
• Synonyms: 2-[(E)-(3-Phenyl-acryloyl)]-benzoic acid;1-ortho-carboxyphenyl-3-phenylprop-2-enone;2-trans(?)-cinnamoyl-benzoic acid;2-trans(?)-Cinnamoyl-benzoesaeure
• CAS NO: 245328-53-4
• Molecular Formula: C16H12O3
• Molecular Weight: 252.269
• Mol File: 245328-53-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(2E)-1-oxo-3-phenyl-2-propenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(2E)-1-oxo-3-phenyl-2-propenyl]-(245328-53-4)
• EPA Substance Registry System: Benzoic acid, 2-[(2E)-1-oxo-3-phenyl-2-propenyl]-(245328-53-4)

Safety Data

• Hazardous Substances Data: 245328-53-4(Hazardous Substances Data)

Upstream product

• 577-56-0 2-acetyl-benzoic acid 
• 100-52-7 benzaldehyde 
• 103935-10-0 ethyl 2-acetylbenzoate 
• 201024-81-9 C,N-diphenylnitrone 
• 3453-63-2 3-methylidenephthalide 

Downstream Products

• 853261-55-9 2-(4-phenyl-2-pyridon-6-yl)benzoic acid 

Relevant articles and documents

Spiroheterocycles from reaction of nitrones with methylene-γ-butyrolactones and some of their rearrangements

Cycloaddition of nitrones 1 with methylene-γ-butyrolactones 2, 3 and 4 afforded spiroadducts 5, 6 and 7 with high selectivity. Mixtures of diastereoisomers were usually obtained, whose structures were established by 1H and 13C NMR spectroscopies or X-ray crystallography. Treatment of spiroadducts in acidic and alkaline media led to different, unexpected and novel rearrangements.

Preparation of 2-pyridone-containing tricyclic alkaloid derivatives as potential inhibitors of tumor cell proliferation by regioselective intramolecular N- and C-acylation of 2-pyridone

A novel and practical preparation of 2-pyridone-containing tricyclic alkaloid derivatives was developed. By regioselective intramolecular N- and C-acylation of 2-(4-aryl-2-pyridon-6-yl)benzoic acid, a pair of structural isomers 2-aryl pyrido[2,1-a]isoindo