245345-55-5Relevant academic research and scientific papers
A novel method for the synthesis of 4'-thiopyrimidine nucleosides using hypervalent iodine compounds.
Nishizono, Naozumi,Baba, Ryosuke,Nakamura, Chika,Oda, Kazuaki,Machida, Minoru
, p. 3692 - 3697 (2007/10/03)
The coupling reactions of cyclic sulfides with a silylated pyrimidine nucleobase using a hypervalent iodine reagent were investigated. The reaction of silylated uracil with cyclic sulfide 12 using PhI=O gave the desired beta-anomer 14 in moderate yield. 4
Nucleosides and nucleotides. 189. Investigation of the stereoselective coupling of thymine with meso-thiolane-3,4-diol-1-oxide derivatives via the Pummerer reaction
Naka, Takashi,Nishizono, Naozumi,Minakawa, Noriaki,Matsuda, Akira
, p. 6297 - 6300 (2007/10/03)
We investigated the stereoselective coupling of thymine with sulfoxides derived from mesothiolane-3,4-diol via the Puremeter reaction. The introduction of 2,4-dimethoxybenzoyl groups to the hydroxyl groups of meso- thiolane-3,4-diol-1-oxide was effective
