245364-50-5

Basic information

• Product Name: (R)-N-Boc-N-o-nitrobenzenesulfonylalanine ethyl ester
• Synonyms: (R)-N-Boc-N-o-nitrobenzenesulfonylalanine ethyl ester
• CAS NO: 245364-50-5
• Molecular Weight: 402.425
• Mol File: 245364-50-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-N-Boc-N-o-nitrobenzenesulfonylalanine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-Boc-N-o-nitrobenzenesulfonylalanine ethyl ester(245364-50-5)
• EPA Substance Registry System: (R)-N-Boc-N-o-nitrobenzenesulfonylalanine ethyl ester(245364-50-5)

Safety Data

• Hazardous Substances Data: 245364-50-5(Hazardous Substances Data)

Upstream product

• 5455-59-4 2-Nitrobenzenesulfonamide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 687-47-8 (S)-Ethyl lactate 
• 198572-71-3 N-(tert-butoxycarbonyl)-2-nitrobenzenesulfonamide 

Downstream Products

• 3082-75-5 D-alanine ethyl ester 

Relevant articles and documents

N-carboalkoxy-2-nitrobenzenesulfonamides: A practical preparation of N- Boc-, N-Alloc-, and N-Cbz-protected primary amines

N-Carboalkoxy-2-nitrobenzenesulfonamides, readily prepared by acylation of 2-nitrobenzenesulfonamide (o-NsNH2), can be alkylated by either conventional or Mitsunobu protocols. Since the o-nosyl group can be deprotected under mild conditions, a variety of N-carboalkoxy derivatives of primary amines may be prepared in excellent yields from the corresponding alcohols and/or halides. In addition, allyloxycarbonyl (Alloc), t- butoxycarbonyl (t-Boc), and benzyloxycarbonyl (Cbz) groups can be deprotected in the presence of the o-nosyl group, allowing the resultant N-alkylated 2- nitrobenzenesulfonamides to be used for further preparation of secondary amines.