245441-87-6

Upstream product

• 18549-40-1 1,2-O-isopropylidene-α-D-glucofuranose 
• 100-58-3 phenylmagnesium bromide 
• 53167-11-6 1,2-O-isopropylidene-α-D-xylo-pentodialdo-1,4-furanose 

Downstream Products

• 144402-16-4 3,5-di-O-benzyl-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentafuranose 
• 245441-88-7 1-[2,2-dimethyl-(6S)-O-(S-methyl dithiocarbonyl)-(3aR,5R,6aR)perhydrofuro[2,3-d][1,3]dioxol-5-yl]-phenylmethyl-(1RS)-O-(S-methyl dithiocarbonate) 
• 321868-56-8 3-(4-nitrophenylcarbonyloxy)-5-phenylmethyl-(3S,5R)-tetrahydrofuran-2-one 
• 245441-89-8 2,2-dimethyl-5-phenylmethyl-(3aR,5R,6aR)-perhydrofuro[2,3-d][1,3]dioxole 
• 203243-30-5 3-hydroxy-5-phenylmethyl-(3R,5R)-tetrahydrofuran-2-one 

Relevant academic research and scientific papers

A concise synthesis of harzialactone A from D-glucose and revision of absolute stereochemistry

Synthesis of 2 by a chiron approach is described starting from monoacetone-D-glucose 4. Absolute stereochemistry of natural harzialactone A 1 (2S,4S) is revised to 2 (2R,4R).