245441-89-8

Upstream product

• 18549-40-1 1,2-O-isopropylidene-α-D-glucofuranose 
• 53167-11-6 1,2-O-isopropylidene-α-D-xylo-pentodialdo-1,4-furanose 
• 6893-65-8 1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose 
• 18439-39-9 2,2-dimethyl-5-phenylmethyl-(3aR,5R,6aR)-perhydrofuro[2,3-d][1,3]-dioxol-(6S)-ol 
• 245441-87-6 1,2-O-isopropylidene-5-C-phenyl-β-L-ido/α-D-gluco-pentofuranose 
• 245441-88-7 1-[2,2-dimethyl-(6S)-O-(S-methyl dithiocarbonyl)-(3aR,5R,6aR)perhydrofuro[2,3-d][1,3]dioxol-5-yl]-phenylmethyl-(1RS)-O-(S-methyl dithiocarbonate) 
• 321868-67-1 2,2-dimethyl-5-phenylmethyl-(3aR,5R,6aR)-perhydrofuro[2,3-d][1,3]dioxol-(6S)-yl-O-(S-methyl dithicarbonate) 

Downstream Products

• 321868-56-8 3-(4-nitrophenylcarbonyloxy)-5-phenylmethyl-(3S,5R)-tetrahydrofuran-2-one 
• 203243-30-5 3-hydroxy-5-phenylmethyl-(3R,5R)-tetrahydrofuran-2-one 

Relevant academic research and scientific papers

Synthesis of harzialactone A and its isomers from D-glucose and assignment of absolute stereochemistry

The synthesis of the marine metabolite (3R,5R)-harzialactone A 1 from D-glucose is described. Syntheses of all the isomers (3S,5R)-2, (3R,5S)-3 and (3S,5S)-4 of 1 are also described and the absolute stereochemistry for the natural product 1 is assigned un

A concise synthesis of harzialactone A from D-glucose and revision of absolute stereochemistry

Synthesis of 2 by a chiron approach is described starting from monoacetone-D-glucose 4. Absolute stereochemistry of natural harzialactone A 1 (2S,4S) is revised to 2 (2R,4R).