24547-45-3

Usage

Uses

Used in Pharmaceutical Industry:
1H-Benzimidazole, 2-chloro-1-phenylis used as a building block in the synthesis of other chemical compounds for the development of new drugs. Its unique structure and properties make it a valuable component in the creation of various pharmaceutical agents.
Used in Agrochemical Industry:
1H-Benzimidazole, 2-chloro-1-phenylis used in the production of agrochemicals, where it serves as a key intermediate in the synthesis of various agrochemical compounds. Its presence in these products contributes to their effectiveness in agricultural applications.
Used as an Antifungal Agent:
1H-Benzimidazole, 2-chloro-1-phenylis used as an antifungal agent due to its ability to inhibit the growth of fungi. Its application in this area helps in controlling fungal infections and maintaining the health of crops and other organisms.
Used as an Anti-Inflammatory Agent:
1H-Benzimidazole, 2-chloro-1-phenylis used as an anti-inflammatory agent, exhibiting potential to reduce inflammation and alleviate associated symptoms. Its incorporation into pharmaceutical formulations can provide relief in conditions characterized by inflammation.
Used in Cancer Treatment:
1H-Benzimidazole, 2-chloro-1-phenylis being investigated for its potential use in the treatment of cancer. Its ability to inhibit the growth of cancer cells makes it a promising candidate for further research and development in oncology. It may be utilized in the development of novel therapeutic agents targeting various types of cancer.

Upstream product

• 14813-85-5 1-phenyl-1,3-dihydrobenzoimidazol-2-one 
• 4857-06-1 2-chloro-1H-benzoimidazole 
• 108-86-1 bromobenzene 
• 591-50-4 iodobenzene 

Downstream Products

• 76463-87-1 2-dimethylamino-1-phenylbenzimidazole 
• 1246385-22-7 C₂₉H₃₃N₅O 
• 97990-76-6 2-(Methylamino)-1-phenyl-1H-benzimidazol 
• 101953-83-7 2-(4-Methyl-piperazin-1-yl)-1-phenyl-1H-benzoimidazole 

Relevant academic research and scientific papers

3-Aryl[1,2,4]triazino[4,3-α]benzimidazol-4(10H)-ones: A new class of selective A1 adenosine receptor antagonists

Radioligand binding assays using bovine cortical membrane preparations and biochemical in vitro studies revealed that various 3-aryl[1,2,4]triazino[4,3-α]benzimidazol-4(10H)-one (ATBI) derivatives, previously reported by us as ligands of the central benzo

Electron transport material and organic light emitting device thereof

The invention discloses an electron transport material and an organic light emitting device thereof, and relates to the technical field of organic photoelectric materials. On the one hand, a benzimidazole group has a very good rigid planar structure and stability; on the one hand, an azacarbazole group has a high triplet energy level (2.96 eV) and a stable energy level, wherein an unsaturated C=Ndouble bond enhances the electron transporting ability; on the other hand, the benzimidazole group combines with the azacarbazole group to increase a conjugated system, a continuous pi-conjugated system brings better electron mobility, thereby having a high electron mobility, due to a large energy gap and the high electron mobility of a compound, the injection of electrons can be effectively ensured, the effect of blocking holes is achieved, and the material can be used as hole blocking materials and electron transporting materials. The material can be applied to the organic light-emitting device, and the device has advantages of low driving voltage and high luminous efficiency, and is superior to existing conventional OLED devices.

Dibenzfluorene compound and organic electroluminescent device thereof

The invention provides a dibenzfluorene compound and an organic electroluminescent device thereof, and relates to the technical field of organic optoelectronic materials. A dibenzfluorene body is connected with an arylamine, substituted or unsubstituted aromatic cyclic condensed imidazole and an oxazole derivative to obtain the dibenzfluorene compound, the dibenzfluorene compound is provided witha bipolar transmission material, so that a hole and an electron are compounded on a luminescence layer, the dibenzfluorene compound has excellent stability and luminescence efficiency, is simple to synthesize, easy to operate and applied to the organic electroluminescent device, serves as a doped material of the luminescence layer and can effectively solve the problems of short service life and low luminescence efficiency of a blue luminescence material in the organic electroluminescent device, and the organic electroluminescent device of the component has the advantages of high luminescence efficiency and long service life.

A containing [...] compound and its organic light-emitting device (by machine translation)

The present invention provides a containing [...] compound and its organic light-emitting device, relates to organic photoelectric material technical field. The invention through [...] fluorene main body connected with the aromatic amine, substituted or not substituted fused imidazole, fused oxazole derivative to obtain a containing [...] compound, is a dual polarity transmission material, holes and electrons in the luminescent layer is of composite, has good stability and light-emitting efficiency, it is simple and easy to operate, and can be applied to organic light-emitting device as the dopant material in the luminescent layer, the organic light-emitting device can effectively solve the blue light-emitting material in the light emitting efficiency is low, the problem of short service life, its organic light emitting device having high luminous efficiency, long service life. (by machine translation)

Benzfluorene-containing compound and organic light-emitting device thereof

The invention provides a benzfluorene-containing compound and an organic light-emitting device thereof, and relates to the technical field of organic optoelectronic materials. A benzfluorene body is connected with arylamine, substituted or non-substituted aromatic nucleus fused imidazole and oxazole derivatives to obtain the benzfluorene-containing compound which is a bipolar transmission material. The benzfluorene-containing compound is beneficial to compounding of cavities and electrons on light emitting layers, has high stability and light emission efficiency, synthesis is simple and easy to operate, and can be applied to the organic light-emitting device to serve as a light emission layer doping material, effectively solving the problems of low light emission efficiency and short service life of blue light-emitting materials in the organic light emitting device. The organic light-emitting device of the benzfluorene-containing compound has the advantages of high light emission efficiency and long service life.

Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists

Melanin concentrating hormone (MCH) is an important mediator of energy homeostasis and plays role in several disorders such as obesity, stress, depression and anxiety. The synthesis and biological evaluation of novel benzimidazole derivatives as MCHR1 antagonists are described. The in vivo proof of principle for weight loss with a lead compound from this series is exemplified.