245524-93-0

Basic information

• Product Name: 4,6-DINITRO INDOLE
• Synonyms: 4,6-DINITRO INDOLE;1H-Indole, 4,6-dinitro-;4,6-Dinitro-1H-Indole
• CAS NO: 245524-93-0
• Molecular Formula: C₈H₅N₃O₄
• Molecular Weight: 207.14
• Mol File: 245524-93-0.mol

Chemical Properties

• Boiling Point: 434.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.649±0.06 g/cm3(Predicted)
• PKA: 12.53±0.30(Predicted)
• CAS DataBase Reference: 4,6-DINITRO INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DINITRO INDOLE(245524-93-0)
• EPA Substance Registry System: 4,6-DINITRO INDOLE(245524-93-0)

Safety Data

• Hazardous Substances Data: 245524-93-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
4,6-DINITRO INDOLE is used as a reagent in chemical synthesis for its ability to participate in various chemical reactions, facilitating the creation of a range of organic compounds.
Used in Pharmaceutical Production:
As a starting material, 4,6-DINITRO INDOLE is utilized in the production of pharmaceuticals, playing a crucial role in the development of new drugs and medicinal compounds.
Used in Dye Manufacturing:
4,6-DINITRO INDOLE is also employed in the manufacturing of dyes, capitalizing on its chemical properties to produce a variety of colorants for different industries.
Used in Explosives Industry:
Due to its high nitrogen content, 4,6-DINITRO INDOLE has potential applications in the field of explosives. Its capacity to act as a component in explosive formulations is of interest, although its use in this field must be approached with strict safety measures.

Upstream product

• 245524-89-4 1-(2,2-dimethoxy)ethyl-2,4,6-trinitrobenzene 
• 7439-89-6 iron 
• 35074-90-9 2,4,6-Trinitrostyrene 
• 2290-14-4 β-(2,4,6-trinitrophenyl)ethanol 
• 296246-80-5 2-(2-amino-4,6-dinitrophenyl)ethanol 
• 312513-83-0 2,3-dihydro-4,6-dinitro-1-(p-toluenesulfonyl)indole 
• 312522-79-5 4,6-dinitro-1-(p-toluenesulfonyl)indole 

Downstream Products

• 868785-31-3 1-benzenesulfonyl-4,6-dinitro-1H-indole 
• 868785-26-6 N-[4-(4,6-dinitro-indole-1-sulfonyl)-phenyl]-acetamide 
• 885518-11-6 C₈H₉N₃ 
• 868785-28-8 [1-(4-acetylamino-benzenesulfonyl)-4-ethoxycarbonylamino-1H-indol-6-yl]-carbamic acid ethyl ester 
• 868785-29-9 [1-(4-amino-benzenesulfonyl)-4-ethoxycarbonylamino-1H-indol-6-yl]-carbamic acid ethyl ester 
• 868785-33-5 (1-benzenesulfonyl-4-ethoxycarbonylamino-1H-indol-6-yl)-carbamic acid ethyl ester 
• 868785-27-7 N-[4-(4,6-diamino-indole-1-sulfonyl)-phenyl]-acetamide 
• 868785-32-4 1-benzenesulfonyl-1H-indole-4,6-diamine 

Relevant articles and documents

Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors

An examination of several amine-substituted analogs of N 1-benzenesulfonylindoles reveals that although they bind at human 5-HT6 serotonin receptors with high affinity, they are likely to bind in a dissimilar manner.

Synthesis of 4,6-dinitroindole from 2,4,6-trinitrotoluene

1-R-4,6-Dinitroindoles 4-6 (R=H, Me, Ts) could be obtained from 2-picrylethanol 1 (readily available from TNT) via selective reduction of ortho-nitro group by N2H4/FeCl3 and subsequent treatment with TsCl, to yield a key i

Conversion of trinitrotoluene into high value compounds

The present invention is directed to the synthesis of useful products from the explosive trinitrotoluene. This substance has a limited shelf life as a reliable explosive and large quantities of it have and will become surplus. Ecologically safe, and preferably commercially useful ways of disposing of it are therefore much to be desired. In the present invention the end products are nitroindoles of the general formula 4-Z1,6-Z2 indole wherein Z1 and Z2 are the same or different and are halo or nitro provided at least one of said groups is nitro.