245539-09-7

Basic information

• Product Name: 1,2-DICHLORO-3-ISOCYANOBENZENE
• Synonyms: HANSA ISN-0058;2,3-DICHLOROPHENYLISOCYANIDE;2,3-DICHLORPHENYLISOCYANIDE;1,2-DICHLORO-3-ISOCYANOBENZENE;Benzene, 1,2-dichloro-3-isocyano- (9CI)
• CAS NO: 245539-09-7
• Molecular Formula: C₇H₃Cl₂N
• Molecular Weight: 172.01
• Product Categories: ISONITRITE
• Mol File: 245539-09-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-DICHLORO-3-ISOCYANOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DICHLORO-3-ISOCYANOBENZENE(245539-09-7)
• EPA Substance Registry System: 1,2-DICHLORO-3-ISOCYANOBENZENE(245539-09-7)

Safety Data

• Hazardous Substances Data: 245539-09-7(Hazardous Substances Data)

Usage

General Description

1,2-Dichloro-3-isocyanobenzene is a chemical compound with the molecular formula C7H3Cl2NO. It is a yellow to brown colored solid that is used in the production of various chemical products, including pesticides and pharmaceuticals. 1,2-DICHLORO-3-ISOCYANOBENZENE is a derivative of benzene, with two chlorine atoms and an isocyanide functional group attached to the benzene ring. It is primarily used as an intermediate in the synthesis of other organic chemicals and is not commonly found in consumer products. 1,2-Dichloro-3-isocyanobenzene is considered to be a hazardous substance and must be handled with proper safety precautions due to its potential toxicity and environmental impact.

Upstream product

• 6327-47-5 2,3-dichloroformanilide 
• 2666-78-6 2,3-dichlorophenyl isocyanide dichloride 

Downstream Products

• 79944-89-1 N-(Bis[Dimethylamino]methylene)-N'-phenyl-4-morpholine carboxamidine 
• 75013-86-4 N-phenyl-2-<1-(2-pyridinyl)ethylidene>hydrazinecyrboselenoamide 
• 4426-68-0 phenyl isoselenocyanate 
• 104379-16-0 N-Phenyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamine 

Relevant articles and documents

Silver-Catalyzed Chemoselective [4+2] Annulation of Two Isocyanides: A General Route to Pyridone-Fused Carbo- and Heterocycles

A silver-catalyzed chemoselective [4+2] annulation of aryl and heteroaryl isocyanides with α-substituted isocyanoacetamides was developed for the facile and efficient synthesis of 2-aminoquinolones, naphthyridines, and phenanthrolines. A mechanism for this multistep domino reaction is proposed on the basis of a13C-labeling experiment, according to which an unprecedented chemoselective heterodimerization of two different isocyanides generates an α-amidoketenimine intermediate, which undergoes 1,3-amino migration to form an α-imidoylketene, followed by 6 π electrocyclization.

Process for the preparation of aryl isocyanide-dichlorides

An improved process for preparation of arylisocyanide dichloride by chlorinating N-arylformamide in the presence of thionyl chloride wherein the improvement comprises preparing the N-arylformamide by formylation of an arylamine having 6 to 12 aryl carbon