245672-23-5

Upstream product

• 245672-17-7 tert-butyl-(+/-)-[7-tert-butoxy-1-[[1-(hydroxymethyl)-2,5-cyclohexadiene-1-yl]methyl]-2-heptynyl][[2-(trimethylsilyl)ethyl]sulfonyl]carbamate, pivalate (ester) 
• 3282-30-2 pivaloyl chloride 
• 245672-15-5 [1-(formylmethyl)-2,5-cyclohexadiene-1-yl]methyl pivalate 
• 245672-12-2 1-(2-tert-butoxyethyl)-2,5-cyclohexadiene-1-methanol 
• 245672-11-1 1-(2-tert-butoxyethyl)-2,5-cyclohexadiene-1-carboxylic acid 
• 245672-14-4 [1-(2-hydroxyethyl)-2,5-cyclohexadiene-1-yl]methyl pivalate 
• 245672-13-3 [1-(2-tert-butoxyethyl)-2,5-cyclohexadiene-1-yl]methyl pivalate 
• 245672-16-6 (+/-)-[1-(8-tert-butoxy-2-hydroxy-3-octynyl)-2,5-cyclohexadiene-1-yl]methyl pivalate 

Downstream Products

• 245672-24-6 tert-butyl-(+/-)-[(Z)-7-tert-butoxy-1-[[1-(hydroxymethyl)-4-oxo-2,5-cyclohexadiene-1-yl]methyl]-2-heptenyl][[2-(trimethylsilyl)ethyl]sulfonyl]carbamate, pivalate (ester) 
• 245672-25-7 tert-butyl-(+/-)-[(Z)-7-tert-butoxy-1-[[1-(hydroxymethyl)-4-oxo-2,5-cyclohexadiene-1-yl]methyl]-2-heptenyl]carbamate, pivalate (ester) 

Relevant academic research and scientific papers

Intramolecular conjugate addition reactions of amines and carbamates to 2,5-cyclohexadien-1-ones: Stereoselective synthesis of perhydroindoles

Intramolecular conjugate addition reactions of 4,4-disubstituted-2,5- cyclohexadien-1-ones are described within the context of possible approaches to manzamine A. Amine 4 provided tricycle 6, with improper relative stereochemistry for use in an approach to manzamine A. Carbamates 25 and 38 gave perhydroindoles 26 and 28 b under conditions of thermodynamic control, respectively, with the proper relative stereochemistry required for manzamine A. Carbamate 25 gave diastereomeric perhydroindole 27 under conditions of thermodynamic control.