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5-Bromo-1H-isochromen-1-one, a member of the isochromenone class, is a chemical compound distinguished by a five-membered carbon ring fused to a benzene ring with a ketone group. The distinctive feature of 5-broMo-1H-isochroMen-1-one is the bromine atom at the 5th position of the carbon ring, which endows it with unique properties. It is widely recognized for its potential as a building block in organic synthesis and in the development of pharmaceuticals, with demonstrated biological activities including anti-cancer, anti-inflammatory, and anti-bacterial properties. 5-broMo-1H-isochroMen-1-one's unique structure and medicinal potential make it a significant subject for ongoing research and development in chemistry and pharmaceuticals.

245677-36-5

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245677-36-5 Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-1H-isochromen-1-one is used as a pharmaceutical intermediate for its potential to be developed into new drugs due to its biological activities. Its anti-cancer properties make it a promising candidate for the treatment of various types of cancer, as it may target and inhibit the growth of cancer cells.
Used in Organic Synthesis:
In the field of organic synthesis, 5-Bromo-1H-isochromen-1-one serves as a key building block for the creation of more complex organic compounds. Its unique structure allows for further chemical modifications, facilitating the synthesis of a variety of molecules with potential applications in different industries.
Used in Anti-Inflammatory Applications:
5-Bromo-1H-isochromen-1-one is utilized as an anti-inflammatory agent, leveraging its ability to reduce inflammation and alleviate symptoms associated with inflammatory conditions. This application can be beneficial in the development of treatments for diseases characterized by chronic inflammation.
Used in Anti-Bacterial Applications:
5-broMo-1H-isochroMen-1-one is also used as an anti-bacterial agent, given its capacity to combat bacterial infections. This makes it a valuable component in the development of new antibiotics, particularly in the face of increasing antibiotic resistance.
Used in Research and Development:
5-Bromo-1H-isochromen-1-one is employed in research and development settings to explore its full potential in medicinal chemistry. Scientists are interested in understanding its mechanism of action, optimizing its synthesis, and identifying new derivatives with improved properties for various therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 245677-36-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,5,6,7 and 7 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 245677-36:
(8*2)+(7*4)+(6*5)+(5*6)+(4*7)+(3*7)+(2*3)+(1*6)=165
165 % 10 = 5
So 245677-36-5 is a valid CAS Registry Number.

245677-36-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-bromoisochromen-1-one

1.2 Other means of identification

Product number -
Other names 5-bromoisocoumarin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:245677-36-5 SDS

245677-36-5Relevant academic research and scientific papers

2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: Reductively triggered release of the parp inhibitor 5- bromoisoquinolinone

Parveen, Ifat,Naughton, Declan P.,Whish, William J. D.,Threadgill, Michael D.

, p. 2031 - 2036 (1999)

5-Chloromethyl-1-methyl-2-nitroimidazole reacted efficiently with the anion derived from 5-bromoisoquinolin-1-one to give 5-bromo-2-((1-methyl-2- nitroimidazol-5-yl)methyl)isoquinolin-1-one. Biomimetic reduction effected release of the 5-bromoisoquinolin-1-one. The 2-nitroimidazol-5-ylmethyl unit thus has potential for development as a general prodrug system for selective drug delivery to hypoxic tissues.

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