24569-37-7

Basic information

• Product Name: C₇H₄ClN₂O₂⁽¹⁺⁾*Cl^(1-)
• Synonyms: C₇H₄ClN₂O₂⁽¹⁺⁾*Cl^(1-)
• CAS NO: 24569-37-7
• Molecular Weight: 219.027
• Mol File: 24569-37-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₇H₄ClN₂O₂⁽¹⁺⁾*Cl^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₇H₄ClN₂O₂⁽¹⁺⁾*Cl^(1-)(24569-37-7)
• EPA Substance Registry System: C₇H₄ClN₂O₂⁽¹⁺⁾*Cl^(1-)(24569-37-7)

Safety Data

• Hazardous Substances Data: 24569-37-7(Hazardous Substances Data)

Upstream product

• 89-54-3 2-chloro-5-aminobenzoic acid 

Downstream Products

• 1135869-46-3 N-methanesulphonyl-5-[5-[l-(2-benzothiazolylhydrazono)ethyl]-2-(N-methylpyrrolyl)]-2-chloro-benzamide 
• 1135871-47-4 2-chloro-5-(2-acetyl-N-methylpyrrolyl)-N-methanesulfonylbenzamide 
• 1135871-46-3 5-(5-acetyl-1-methyl-1H-pyrrol-2-yl)-2-chlorobenzoic acid 
• 1135871-42-9 5-(5-acetylfuran-2-yl)-2-chlorobenzoic acid 
• 184163-49-3 2-chloro-5-hydrazinobenzoic acid hydrochloride 

Relevant articles and documents

BENZOTHIAZOLE COMPOUNDS

The present invention relates to benzothiazole compounds that mimic the activity of BH3 only proteins and are capable of binding to and neutralizing pro survival Bcl 2 proteins. The invention also relates to the use of such compounds in the regulation of cell death or cell survival and the treatment and/or prophylaxis of diseases or conditions associated with the deregulation of cell death or cell survival.

Dihydrodipyrazolopyridinylbenzamide and -sulfonamide inhibitors of B7-1

The present invention provides a compound of formula I and the use thereof for the immunotherapeutic treatment of transplant rejection or autoimmune disease.