245729-74-2Relevant academic research and scientific papers
A diene transmissive diels-alder strategy for oxygenated nor-steroid and triterpenoid skeletons
Woo, Simon,Legoupy, Stéphanie,Parra, Stéphanie,Fallis, Alex G.
, p. 1013 - 1016 (2008/02/09)
(matrix presented) A diene transmissive cycloaddition strategy for the synthesis of tetracyclic skeletons is described. Initially both L-gulonolactone and L-arabinose were converted independently to related acetal aldehydes 13 and 14. A pentadienyl indium
Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B
Laurin, Patrick,Ferroud, Didier,Klich, Michel,Dupuis-Hamelin, Claudine,Mauvais, Pascale,Lassaigne, Patrice,Bonnefoy, Alain,Musicki, Branislav
, p. 2079 - 2084 (2007/10/03)
The design, synthesis, and in vitro biological activity of a series of novel coumarin inhibitors of gyrase B is presented. Replacement of the 3- acylamino residue (3-NHCOR) of coumarin drags with reversed isosteres C(=O)R, C(=N-OR)R', COOR, CONHR and CONH
A CONCISE SYNTHESIS OF PATULIN FROM ARABINOSE
Gill, G. Bryon,Pattenden, Gerald,Stapleton, Alan
, p. 2875 - 2878 (2007/10/02)
Conversion of arabinose (5) to the protected ketone (7), followed by Wittig condensation to (9), acid catalysed cyclisation (to 10), and dehydration, provides a brief synthesis of the fungal metabolite patulin (1), produced by Penicillium and Aspergilius
