24580-61-8Relevant academic research and scientific papers
Alkynylation of carbonyl compounds with terminal acetylenes promoted by ZnCl2 and Et3N: Simple, mild and efficient preparation of propargylic alcohols
Jiang, Biao,Si, Yu-Gui
, p. 8323 - 8325 (2002)
A mild and efficient addition of terminal acetylenes to carbonyl compounds in the presence of ZnCl2 and Et3N gives propargylic alcohols in good to high yields.
Acid catalysed rearrangement of isobenzofurans to angularly fused phthalides
Chinta, Bhavani Shankar,Gandhi, Soniya,Baire, Beeraiah
supporting information, p. 4715 - 4719 (2019/05/24)
An acid catalysed, cascade process for the construction of angularly fused polycyclic phthalides from isobenzofurans under transition metal free conditions has been reported. This process is very general for diverse gem-disubstituted isobenzofuran substrates. Control experiments supported the mechanism as the nucleophilic attack of the carboxylate onto the acid activated furan ring for the simultaneous ring closing-ring opening cascade followed by dehydration. This method serves as a greener alternative for the synthesis of angularly fused polycyclic phthalides.
A new entry in catalytic alkynylation of aldehydes and ketones: Dual activation of soft nucleophiles and hard electrophiles by an indium(III) catalyst
Takita, Ryo,Fukuta, Yuhei,Tsuji, Riichiro,Ohshima, Takashi,Shibasaki, Masakatsu
, p. 1363 - 1366 (2007/10/03)
(Chemical Equation Presented). A new entry in catalytic alkynylation of carbonyl compounds was developed in which dual activation of both soft nucleophiles (terminal alkynes) and hard electrophiles (aldehydes and ketones) is achieved using an indium(III)
Efficient routes to cyclic 2,3-epoxyalcohols from cycloalkenyl ketones, via cycloalkenyl alcohols
Marson,Walker,Pickering,Harper,Wrigglesworth,Edge
, p. 10317 - 10338 (2007/10/02)
The minimising of torsional strain and non-bonding interactions is proposed as the explanation of high diastereoselectivity observed in the epoxidation of cycloalkenyl alcohols, reported for twenty three examples. The resulting 2,3-epoxyalcohols are key i
