24581-96-2

Upstream product

• 96-32-2 bromoacetic acid methyl ester 
• 635-93-8 5-chlorosalicyclaldehyde 

Downstream Products

• 14440-47-2 (4-chloro-2-formylphenoxy)acetic acid 
• 6386-63-6 2-hydroxymethyl-4-chlorophenyloxyacetic acid 
• 99070-85-6 (4-chloro-2-hydroxymethyl-phenoxy)-acetic acid methyl ester 
• 1001335-15-4 E/Z-[4-chloro-2-(6-chloro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-phenoxy]-acetic acid methyl ester 
• 915697-45-9 (E)-3-[2-(2-carboxymethoxy-5-chloro-benzyl)-phenyl]-acrylic acid 
• 915697-44-8 (2-bromomethyl-4-chloro-phenoxy)-acetic acid methyl ester 
• 1370710-80-7 methyl 3-[2-(carbomethoxymethyloxy)-5-chloro]-phenyl-3-hydroxy-2-methylenepropanoate 
• 1370710-87-4 methyl 3-acetoxy-3-[2-(carbomethoxymethyloxy)-5-chloro]phenyl-2-methylenepropanoate 

Relevant academic research and scientific papers

3,3'-SPIROINDOLINONE DERIVATIVES AND THEIR USE FOR CANCER

There are provided compounds of the formula (I) or a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W?,V, V?, V", R1, R2 and R3 are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer

Spiroindolinone Derivatives

There are provided compounds of the formula and pharmaceutically acceptable salts and esters and enantiomers thereof wherein W, X, X′, Y, V, V′, A, B and R are as described herein. The compounds have utility as antiproliferative agents, especially, as anticancer agents.

ORGANIC COMPOUNDS

A compound of formula (I); in free or pharmaceutically acceptable salt form, where R1, R2, R3, R4, R5, m, n, w, X, Y and Q have the meanings as indicated in the specification, are useful for treating conditions mediated by the CRTh2 receptor, especially inflammatory or obstructive airways diseases.