24582-71-6Relevant academic research and scientific papers
EGFR/HER-2 inhibitors: Synthesis, biological evaluation and 3D-QSAR analysis of dihydropyridine-containing thiazolinone derivatives
Ren, Yu-Jia,Wang, Zhong-Chang,Zhang, Xin,Qiu, Han-Yue,Wang, Peng-Fei,Gong, Hai-Bin,Jiang, Ai-Qin,Zhu, Hai-Liang
, p. 21445 - 21454 (2015/03/30)
A series of dihydropyridine containing thiazolinone derivatives (4a-4r) have been designed, synthesized and their biological activities evaluated as potential EGFR and HER-2 kinase inhibitors and in tumor cell antiproliferation. The synthesized compounds
Anti-tubercular, antioxidant and in vitro anti-inflammatory activity of some newly synthesized chalcones
Alam, Shadab,Panda, Rakesh,Kachroo, Monica
, p. 440 - 443 (2014/05/06)
A series of chalcones of 4-acetyl pyridines and substituted aryl aldehydes have been synthesized and evaluated for antitubercular, antioxidant and anti-inflammatory activity. The structures of the synthesized compounds have been confirmed by IR, 1/s
Synthesis and biological activities of some new pyrazole derivatives from chalcones
Kachroo, Monica,Yadav, Yadavendra,Devi, Kalpana
, p. 141 - 144 (2019/01/21)
Nitrogen containing heterocyclic detivatives synthesized from chalcones have exhibited anti-inflammatory, antioxidant, antitubercular, antibacterial activities. Therefore an attempt has been made to synthesize chalcones by the reaction of 4-acetylpyridine
Synthesis of 4-pyrido-6-aryl-2-substituted amino pyrimidines as a new class of antimalarial agents
Agarwal, Anu,Srivastava, Kumkum,Puri,Chauhan, Prem M.S.
, p. 6226 - 6232 (2007/10/03)
A series of 2,4,6-trisubstituted pyrimidines were synthesized and evaluated for their in vitro antimalarial activity against Plasmodium falciparum. Of the 18 compounds synthesized, 14 compounds showed MIC in the range of 0.25-2 μg/mL. These compounds are
