2460-49-3

Usage

Uses

Used in Agrochemical and Pharmaceutical Production:
4,5-Dichloroguaiacol is used as an intermediate in the synthesis of various agrochemicals and pharmaceuticals, contributing to the development of products that address agricultural and health-related needs.
Used in Cancer Treatment Research:
4,5-Dichloroguaiacol is being studied for its potential as a diagnostic and therapeutic agent in cancer treatments, indicating its possible role in the advancement of medical science and patient care.
Used in Chemical Synthesis:
As a versatile chemical, 4,5-Dichloroguaiacol is utilized in chemical synthesis processes across different industries, highlighting its importance in the creation of a wide range of products.

InChI:InChI=1/C7H6Cl2O2/c1-11-7-3-5(9)4(8)2-6(7)10/h2-3,10H,1H3

Upstream product

• 3428-24-8 4,5-dichlorocatechol 
• 90-05-1 2-methoxy-phenol 
• 120-80-9 benzene-1,2-diol 
• 77-78-1 dimethyl sulfate 
• 1120310-43-1 4-chloro-6,6-dimethoxycyclohexa-2,4-dienone 
• 16766-30-6 4-Chloroguaiacol 
• 74-88-4 methyl iodide 

Downstream Products

• 874487-57-7 2-(4,5-dichloro-2-methoxy-phenoxy)-propionic acid 
• 2772-46-5 4,5-Dichlor-brenzcatechindimethylether 
• 56913-12-3 (4,5-dichloro-2-methoxy-phenoxy)-acetic acid 
• 63709-65-9 4,5-dichloro-2-(2',3',5',6'-tetrachlorophenoxy)anisole 
• 93313-89-4 ω-<4.5-Dichlor-2-methoxy-phenoxy>-acetoveratron 
• 92106-25-7 Glycolaldehyd-(4,5-dichlor-guajacyl)-aether-diaethyl-acetal 
• 85430-15-5 4,5-Dichloroguaiacol acetate 
• 90348-66-6 Glycolaldehyd-(4,5-dichlor-guajacyl)-aether 
• 93408-27-6 α-<3,4-Dimethoxy-phenyl>-aethylen-glykol-β-<4,5-dichlor-guajacyl>-aether 
• 1354200-67-1 2-(3-(4,5-dichloro-2-methoxyphenoxy)-2-hydroxypropyl)-6-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 1354200-94-4 2-((4,5-dichloro-2-methoxyphenoxy)methyl)oxirane 
• 63709-59-1 4,5-dichloro-2-(2',3',5',6'-tetrachlorophenoxy)phenol 
• 78576-70-2 4,5-Dichloro-2-(2,3,4,5,6-pentachlorophenoxy)-phenol 
• 52780-56-0 2-Aminomethyl-3,4-dichloro-6-methoxy-phenol; hydrochloride 

Relevant academic research and scientific papers

Unanticipated participation of HCl in nucleophilic chlorination reaction: Expedient route to meta chlorophenols

o-Quinone monoketals participated in a 1,4-addition reaction with HCl furnishing m-chlorophenols in high yields. Several readily available o-quinone monoketals were selected to display the generality of this serendipitous and unprecedented reaction and the results are presented herein.

CFBSA: a novel and practical chlorinating reagent

A structurally simple, highly reactive chlorinating reagent, N-chloro-N-fluorobenzenesulfonylamine (CFBSA), was conveniently prepared from inexpensive Chloramine B in high yield. A wide range of substrates were chlorinated with it to obtain products in good to high yields and appropriate selectivity.

Chemical Compounds

The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

Synthesis, X-ray structure determination, and formation of 3,4,5-trichloroquaiacol occuring in kraft pulp spent bleach liquors

3,4,5-Trichloroquaiacol, which is formed during bleaching of chemical pulp and shown to bioaccumulate in fish, has been synthesized.The structure of the compound has been determined by means of X-ray analysis.The values of the 13C nmr chemical shifts and melting point differ from those previously reported.A reaction mechanism is suggested for the formation of 3,4,5- and 4,5,6-trichloroguaiacol.