246028-15-9Relevant articles and documents
Synthesis of enantiomerically pure 2',3',5'-trideoxy-4'- [(diethoxyphosphoryl)difluoromethyl]thymidine analogues
Arnone, Alberto,Bravo, Pierfrancesco,Frigerio, Massimo,Mele, Andrea,Vergani, Barbara,Viani, Fiorenza
, p. 2149 - 2157 (2007/10/03)
D- and L-(diethoxyphosphoryl)difluoromethyl nucleoside analogues 10 have been synthesized using the building block approach, starting from chiral fluorinated molecules. The key steps of the synthetic sequence were condensation of 2-methyl-5-(4-methylpheny