24610-33-1

Basic information

• Product Name: 7-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID
• Synonyms: 7-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID;1H-INDOLE-2-CARBOXYLIC ACID,7-METHOXY-
• CAS NO: 24610-33-1
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.18
• Mol File: 24610-33-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 187-188°
• Boiling Point: 447.6°Cat760mmHg
• Flash Point: 224.5°C
• Appearance: /
• Density: 1.381g/cm³
• Vapor Pressure: 8.54E-09mmHg at 25°C
• Refractive Index: 1.677
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.37±0.30(Predicted)
• CAS DataBase Reference: 7-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID(24610-33-1)
• EPA Substance Registry System: 7-METHOXY-1H-INDOLE-2-CARBOXYLIC ACID(24610-33-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 24610-33-1(Hazardous Substances Data)

Usage

General Description

7-Methoxy-1H-indole-2-carboxylic acid is a chemical compound with the molecular formula C10H9NO3. It is an indole derivative with a carboxylic acid group and a methoxy group attached to the aromatic ring. This chemical is commonly used as a building block in the synthesis of various pharmaceutical compounds and organic molecules. It has potential applications in the pharmaceutical industry, specifically in the development of new drugs and pharmaceutical products. Additionally, this compound has been studied for its potential biological activities and pharmacological properties, making it an important compound for research and development in the field of medicinal chemistry.

InChI:InChI=1/C10H9NO3/c1-14-8-4-2-3-6-5-7(10(12)13)11-9(6)8/h2-5,11H,1H3,(H,12,13)

Upstream product

• 82204-33-9 2-nitro-3-methoxy-α-(oxo)benzenoacetic acid 
• 84638-71-1 7-methoxy-1H-indole-2-carboxylic acid methyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 20538-12-9 ethyl 7-methoxy-1H-indole-2-carboxylate 

Downstream Products

• 3189-22-8 7-methoxy-1H-indole 
• 1394078-55-7 (7-methoxy-1H-indol-2-yl)-(4-methyl-1,4-diazepan-1-yl)methanone 
• 53512-46-2 2-methyl-7-methoxy indole 
• 812653-09-1 16-[7-methoxy-1-(4-methoxybenzenesulfonyl)-1H-indol-3-yl]hexadecan-1-ol 
• 812652-85-0 7-methoxy-1-(4-methoxybenzenesulfonyl)-1H-indole-3-carbaldehyde 
• 109021-59-2 7-methoxy-1H-indole-3-carbaldehyde 

Relevant articles and documents

INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME

An indole derivative represented by the following general formula (1) : wherein at least one of R1, R2, R3, and R4 represents an alkoxy group containing 1 to 20 carbon atoms, and other groups of the R1, R2, R3, and R4 represent hydrogen, an alkyl group containing 1 to 6 carbon atoms, acetyl group, or hydroxyl group; and either one of X and Y represents -(CH2)nOH wherein n is an integer of 0 to 30, and the other one of the X and Y represents hydrogen atom; or a salt thereof; and a drug and an agent for promoting differentiation of a stem cell containing such indole derivative or its salt as an effective component. The indole derivative (1) of the present invention has action of inducing differentiation of neural stem cell specifically into a neuron, and this indole derivative is useful as a prophylactic or therapeutic drug for brain dysfunction or neuropathy caused by loss or degeneration of the neuron.

USE OF INDOLYL DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT ALLERGIC RHINITIS

A method to treat allergic rhinitis is disclosed in which patients are administered certain indolyl compounds.