246180-23-4Relevant academic research and scientific papers
Asymmetric dihydroxylations of aromatic cyclopropylidenes
Diffendal, Jason M.,Filan, John,Spoors, P. Grant
, p. 6137 - 6139 (1999)
A number of aromatic cyclopropylidenes have been converted to diols using the Sharpless asymmetric dihydroxylation (AD) procedure. The enantiomeric ratios were determined by chiral phase HPLC by comparison with their racemates.
The First Example of Asymmetric Dihydroxylation of Cyclopropylidene Derivatives --- An Enantioenriched Formal Total Synthesis of (-)-Filiformin
Nemoto, Hideo,Miyata, Junji,Hakamata, Hideki,Fukumoto, Keiichiro
, p. 1055 - 1058 (2007/10/02)
The first example of asymmetric dihydroxylation (AD) of the cyclopropylidene derivatives 4a-e followed by enantiospecific 1,2-rearrangement of the resulted diols 5a-e to give the optically active cyclobutanones 7a-e was reported.The synthesis of 7e consti
