24621-54-3Relevant academic research and scientific papers
Novel heterobimetallic catalysts for asymmetric Michael reactions
Velmathi,Swarnalakshmi,Narasimhan
, p. 113 - 117 (2003)
The newly developed chiral catalysts 1 and 2 show opposite enantioselectivity in Michael addition reactions of cyclic enones and malonates resulting in the production of both enantiomers of products in good chemical yield and enantiomeric excess. 27
NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS
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Paragraph 0361; 0364, (2019/11/04)
The present invention relates to novel phosphorous (V) (P(V)) reagents, methods for preparing thereof, and methods for preparing organophosphorous (V) compounds by using the novel reagents.
Catalyst-free conjugate addition of thioacids to activated olefins accelerated in water
Marjani, Katayoun,Khalesi, Maryam,Ashouri, Akram,Jalali, Aazam,Ziyaei-Halimehjani, Azim
experimental part, p. 451 - 458 (2011/04/16)
Michael addition of thioacetic and thiobenzoic acids to activated olefins was investigated in the presence of water under catalyst-free conditions. This process, in addition to being green, has an excellent yield. With simple filtration, high-quality products were obtained on a large scale. Competitive dithiane formation and ester cleavage were not observed. Also, excellent yield was obtained using this simple process for the final step of spironolactone synthesis.
Michael addition reaction of thioacetic acid (AcSH) to conjugated alkenes under solvent- and catalyst-free conditions
Sobhani, Sara,Rezazadeh, Soodabeh
experimental part, p. 2076 - 2084 (2010/12/19)
A new and convenient procedure has been developed for the Michael addition reaction of thioacetic acid (AcSH) to a variety of conjugated alkenes under solvent- and catalyst-free conditions. These reactions proceeded in 5-60 min and produced the desired products in good to high yields. Copyright Taylor & Francis Group, LLC.
Organocatalytic enantioselective Michael addition of thioacetic acid to enones
Li, Hao,Zu, Liansuo,Wang, Jian,Wang, Wei
, p. 3145 - 3148 (2007/10/03)
An enantioselective, organocatalytic Michael addition reaction of thioacetic acid with enones has been developed. The process, catalyzed by a chiral bifunctional amine thiourea, furnishes products in excellent yields with up to 63% ee.
Effect of microwaves in the chiral switching asymmetric Michael reaction
Narasimhan,Velmathi
, p. 256 - 262 (2007/10/03)
Highly enantioselective Michael reactions of malonates with cyclic enones are achieved in remarkably less time under microwave irradiation using newly developed heterobimetallic catalysts.
