246231-77-6 Usage
General Description
(S)-1-[(R)-2-(dicyclohexylphosphino)-ferrocenyl]ethyldicyclohexylphosphine is an organometallic compound used as a ligand in transition metal catalysis and asymmetric synthesis. It contains a ferrocene moiety, which provides stability and electron-donating properties, and two dicyclohexylphosphine groups, which serve as coordinating sites for transition metals. The compound is chiral, with an (R) configuration at the ferrocene center and an (S) configuration at the ethyl group. This chiral configuration allows the compound to selectively interact with certain substrates and transition metals, making it a valuable tool in the synthesis of chiral molecules and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 246231-77-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,6,2,3 and 1 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 246231-77:
(8*2)+(7*4)+(6*6)+(5*2)+(4*3)+(3*1)+(2*7)+(1*7)=126
126 % 10 = 6
So 246231-77-6 is a valid CAS Registry Number.
InChI:InChI=1/C31H51P2.C5H5.Fe/c1-25(32(26-15-6-2-7-16-26)27-17-8-3-9-18-27)30-23-14-24-31(30)33(28-19-10-4-11-20-28)29-21-12-5-13-22-29;1-2-4-5-3-1;/h14,23-29H,2-13,15-22H2,1H3;1-5H;/t25-;;/m0../s1
246231-77-6Relevant articles and documents
Rhodium-Catalyzed Asymmetric Allylation of Malononitriles as Masked Acyl Cyanide with Allenes: Efficient Access to β,γ-Unsaturated Carbonyls
Grugel, Christian P.,Breit, Bernhard
supporting information, p. 15223 - 15226 (2018/09/25)
A rhodium-catalyzed regio- and enantioselective intermolecular allylation of malononitriles as masked acyl cyanides (MAC) with terminal and symmetrical internal allenes is reported. A RhI/Josiphos catalytic system combined with subsequent oxidative degradation of the primary adducts enables a straightforward access to α-branched, β,γ-unsaturated carbonyl compounds. The present protocol exhibits perfect atom economy in the allylation step and is characterized by a great functional group compatibility. Furthermore, the use of α-substituted malononitriles allowed for the construction of all-carbon quaternary centers.