24629-32-1Relevant academic research and scientific papers
Transformation of trans -4-aryl-3-chloro-1-(2-chloroethyl)azetidin-2-ones into 3-aryl-2-(ethylamino)propan-1-ols via intermediate 1-(1-aryl-2-chloro-3- hydroxypropyl)aziridines and trans -2-aryl-3-(hydroxymethyl)aziridines
Mollet, Karen,D'Hooghe, Matthias,De Kimpe, Norbert
, p. 264 - 269 (2011/03/20)
trans-4-Aryl-3-chloro-1-(2-chloroethyl)azetidin-2-ones, prepared through cyclocondensation of chloroketene and the appropriate imines in a diastereoselective way, were unexpectedly transformed into 3-aryl-2-(ethylamino) propan-1-ols using LiAlH4/sub
