24630-85-1

Usage

Uses

Used in Pharmaceutical Industry:
(3-CHLORO-4-METHOXY-PHENYL)-HYDRAZINE is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of products with different therapeutic applications.
Used in Chemical Industry:
(3-CHLORO-4-METHOXY-PHENYL)-HYDRAZINE is used as a building block in the production of dyes and other returned substances. Its reactivity and structural features make it a valuable component in the synthesis of these compounds.
Used in Pesticide Industry:
(3-CHLORO-4-METHOXY-PHENYL)-HYDRAZINE is used as a precursor in the development of certain pesticides. Its chemical properties contribute to the effectiveness of these agricultural chemicals.

Upstream product

• 6329-90-4 4-methoxy-3-chloroaniline hydrochloride 
• 144-55-8 sodium hydrogencarbonate 
• 5345-54-0 3-chloro-4-methoxyaniline 

Downstream Products

• 1273318-89-0 1-(3-chloro-4-hydroxyphenyl)-8-{[5-chloro-2-(4-methylpiperazin-1-yl)isonicotinoyl]amino}-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide 
• 1273318-68-5 C₂₅H₁₈Cl₃N₅O₃ 

Relevant academic research and scientific papers

Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship

Installation of sites for metabolism in the lead compound PHA-767408 was the key focus of the IKK-2 inhaled program. This paper reports our efforts to identify a novel series of aminopyridinecarboxamide-based IKK-2 inhibitors, which display low nanomolar potency against IKK-2 with long duration of action (DOA), and metabolically labile to phase I and/or phase II metabolizing enzymes with potential capability for multiple routes of clearance. Several compounds have demonstrated their potential usefulness in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Synthesis of COX-2 and FAAH inhibitors

Methods for preparing indoles that are useful COX-2 inhibitors and intermediates useful in such methods are described.

Pyridazino quinoline compounds

The invention relates to pyridazinoquinoline compounds of the formulas B and B′ wherein Ring A is selected from an ortho fused aromatic or heteroaromatic five- or six-membered ring and R1, R3and R4are substituents selected from halo, OH, OCF3, NO2, CN, NR′R″, SO2NR′R″, SOmR′alkyl, and a variety of alkyl, aryl, heterocyclic and heteroaryl groups, to pharmaceutical compositions containing them and to methods utilizing them for the treatment of neurological disorders.

Pyridazion quinoline compounds

The present invention relates to compounds, pharmaceutical compositions and methods of using compounds of formula (I) in the treatment and/or prevention of certain diseases or conditions. In formula (I), A is chosen from ortho substituted aryl or heteroaryl species, X is chosen from --OH, --SH, NHR and R 1 or R 2 is chosen from --(CH 2) n L wherein L may be selected from a variety of substituents including aryl, heteroaryl and heterocyclic groups. The compounds are useful in treating and/or preventing neurological disorders associated with excitatory amino acids. STR1