24641-36-9

Basic information

• Product Name: (+/-)-hinokinin
• CAS NO: 24641-36-9
• Molecular Weight: 354.359
• Mol File: 24641-36-9.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: (+/-)-hinokinin(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-hinokinin(24641-36-9)
• EPA Substance Registry System: (+/-)-hinokinin(24641-36-9)

Safety Data

• Hazardous Substances Data: 24641-36-9(Hazardous Substances Data)

Upstream product

• 120-57-0 piperonal 
• 24562-96-7 (2R*,3S*)-2,3-bis(3′,4′-methylenedioxybenzyl)butane-1,4-diol 
• 53762-69-9 5-(2-iodoethyl)-3,4-methylenedioxybenzene 
• 1383105-45-0 dimethyl 2-(2-(3,4-methylenedioxyphenyl)ethylidene)malonate 
• 1383105-47-2 dimethyl 2-(2-(3,4-methylenedioxyphenyl)-1-(pivaloyloxymethyl)ethyl)malonate 
• 1383105-49-4 methyl 4-(3,4-methylenedioxyphenylmethyl)-2-oxotetrahydrofuran-3-carboxylate 
• 1383105-53-0 dimethyl [2-(1,3-benzodioxol-5-yl)ethyl]malonate 
• 1383105-55-2 C₂₀H₂₀O₆Se 
• 102001-95-6 trans-(+/-)-3,4-bis<(1,3-benzodioxol-5-yl)methyl>dihydro-2,5-furandione 
• 80483-34-7 4-(1,3-benzodioxol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one 
• 2606-51-1 3,4-Methylenedioxybenzyl bromide 
• 57420-27-6 2-piperonylsuccinic acid 
• 84736-29-8 dimethyl 2-[benzo(d)(1,3)dioxol-5-ylmethyl]succinate 
• 125130-64-5 bis(3,4-methylendioxybenzylidene)succinic acid 

Downstream Products

• 81410-43-7 ariensin 

Relevant articles and documents

A short synthesis of biologically active lignan analogues

β-Benzyl-γ-butyrolactones were synthesized in four transition metal catalysed reactions from butynediol, and alkylated to afford new, biologically active lignan analogues.

Modular synthesis and biological investigation of 5-hydroxymethyl dibenzyl butyrolactones and related lignans

Dibenzyl butyrolactone lignans are well known for their excellent biological properties, particularly for their notable anti-proliferative activities. Herein we report a novel, efficient, convergent synthesis of dibenzyl butyrolactone lignans utilizing the acyl-Claisen rearrangement to stereoselectively prepare a key intermediate. The reported synthetic route enables the modification of these lignans to give rise to 5-hydroxymethyl derivatives of these lignans. The biological activities of these analogues were assessed, with derivatives showing an excellent cytotoxic profile which resulted in programmed cell death of Jurkat T-leukemia cells with less than 2% of the incubated cells entering a necrotic cell death pathway.

Synthesis, anti-virus and anti-tumour activities of dibenzylbutyrolactone lignans and their analogues

An efficient synthesis of dibenzylbutyrolactone lignans and their analogues has been developed. Based on a Stobbe condensation of piperonal or veratraldehyde with diethylsuccinate and alkylation with 3,4- methylenedioxybenzyl bromide to give the skeleton