24646-25-1 Usage
Uses
Used in Pharmaceutical and Agrichemical Industries:
Methyl 2-(4-nitrophenyl)butanoate is used as a key intermediate in the synthesis of various pharmaceuticals and agrichemicals for its versatile chemical properties, contributing to the development of new drugs and pesticides.
Used in Perfumery and Flavoring Industry:
Leveraging its strong aroma, methyl 2-(4-nitrophenyl)butanoate is employed as a fragrance ingredient and flavoring agent in the production of perfumes and flavorings, enhancing the sensory experience of consumer products.
Used in Dye and Pigment Manufacturing:
Methyl 2-(4-nitrophenyl)butanoate serves as an intermediate in the manufacturing of dyes and pigments, playing a crucial role in the creation of vibrant colors and shades for various applications, including textiles, plastics, and printing inks.
Safety Precautions:
Given its potentially hazardous nature, methyl 2-(4-nitrophenyl)butanoate should be handled with care to minimize the risk of skin, eye, and respiratory irritation. Proper safety measures, including the use of personal protective equipment and adherence to safety guidelines, are essential during its production, storage, and use.
Check Digit Verification of cas no
The CAS Registry Mumber 24646-25-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,6,4 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 24646-25:
(7*2)+(6*4)+(5*6)+(4*4)+(3*6)+(2*2)+(1*5)=111
111 % 10 = 1
So 24646-25-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO4/c1-3-10(11(13)16-2)8-4-6-9(7-5-8)12(14)15/h4-7,10H,3H2,1-2H3
24646-25-1Relevant academic research and scientific papers
Resolution of 4-Cyano-4-(4-nitrophenyl)hexanoic acid: Synthesis of (R) and (S)-3-(4-aminophenyl)-3-ethylpiperidine- (aminoglutethimide)
Achmatowicz, Osman,Malinowska, Iwona,Szechner, Barbara,Maurin, Jan K.
, p. 7917 - 7928 (2007/10/03)
Using (R)- or (S)-1-phenylethylamine as a resolving agent, (R)- and (S)-4-cyano-4-(4-nitrophenyl)hexanoic acids have been isolated. Cyclization of each enantiomer, followed by reduction of the nitro group, afforded (R)- and (S)-aminoglutethimide of high (>99% ee enantiomeric purity, respectively. The absolute configuration of (R)-(+)-3-(4-nitrophenyl)-3-ethylpiperidine-2,6-dione was solved by X-ray single crystal analysis thus establishing the (R)-configuration of the dextrorotatory aminoglutethimide. Attempted resolution of the other precursor of aminoglutethimide, 4-cyano-2-ethyl-(4-nitrophenyl)butanoic acid with (S)-1-phenylethylamine led to the formation of the double salt. Its crystal structure was elucidated by X-ray crystallographic analysis.
Nucleophilic substitution process
-
, (2008/06/13)
Nitroarylacetic acid esters are prepared by reacting a nitroaromatic compound which is devoid of halogen on the aromatic ring carrying a nitro group with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base so that the ester undergoes a nucleophilic substitution on an unsubstituted ring carbon of the nitroaromatic compound during which an alpha-substituent functions as a leaving group. Nitrobenzene acetic acids and their esters are useful intermediates for the synthesis of pharmaceuticals.
