24647-62-9

Basic information

• Product Name: 3-(2-METHYL-IMIDAZOL-1-YL)-PROPIONIC ACID
• Synonyms: Albb-008430;2-METHYL-1H-IMIDAZOLE-1-PROPIO【MFCD00234356】;3-(2-methyl-1H-imidazol-1-yl)propanoic acid(SALTDATA: 0.65H2O);3-(2-methyl-1-imidazolyl)propanoic acid;3-(2-methyl-3H-imidazol-1-ium-1-yl)propanoate;3-(2-methyl-3H-imidazol-1-ium-1-yl)propionate;3-(2-methylimidazol-1-yl)propanoic acid;RARECHEM AL BO 1555
• CAS NO: 24647-62-9
• Molecular Formula: C7H10N2O2
• Molecular Weight: 154.17
• Mol File: 24647-62-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 112-114 °C(Solv: 1-butanol (71-36-3))
• Boiling Point: 261°C at 760 mmHg
• Flash Point: 97.2°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0.0119mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: 2-8°C
• PKA: 4.21±0.10(Predicted)
• Water Solubility: Soluble in water (250 mg/L).
• CAS DataBase Reference: 3-(2-METHYL-IMIDAZOL-1-YL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-METHYL-IMIDAZOL-1-YL)-PROPIONIC ACID(24647-62-9)
• EPA Substance Registry System: 3-(2-METHYL-IMIDAZOL-1-YL)-PROPIONIC ACID(24647-62-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 24647-62-9(Hazardous Substances Data)

Usage

Uses

Used as pharmaceutical intermediate.

InChI:InChI=1/C9H9ClO2/c1-2-12-8-5-3-4-7(6-8)9(10)11/h3-6H,2H2,1H3

Upstream product

• 18999-48-9 ethyl 3-(2-methyl-1H-imidazol-1-yl)propanoate 

Relevant articles and documents

Synthesis and biological evaluation of novel 99mtc-labelled bisphosphonates as superior bone imaging agents

A series of novel zoledronic acid (ZL) derivatives 1-hydroxy-3-(2-methyl- 1H-imidazol-1-yl)propane-1,1-diyldiphosphonic acid (MIPrDP), 1-hydroxy-4-(2-methyl-1H-imidazol-1-yl)butane-1,1-diyldiphosphonic acid (MIBDP), and 1-hydroxy-5-(2-methyl-1H-imidazol-1-yl)pentane-1,1-diyldiphosphonic acid (MIPeDP) were prepared and successfully labeled with 99mTc in high labeling yields. The in vitro stability and in vivo biodistribution of 99mTc-MIPrDP, 99mTc-MIBDP and 99mTc-MIPeDP were investigated and compared. The biodistribution studies indicate that the radiotracer 99mTc-MIPrDP has highly selective uptake in the skeletal system and rapid clearance from soft tissues. The present findings indicate that 99mTc-MIPrDP holds great potential for use in bone imaging.