18999-48-9

Usage

Uses

Used in the Fragrance and Flavor Industry:
ETHYL 3-(2-METHYL-1H-IMIDAZOL-1-YL)PROPANOATE is used as a synthetic flavoring agent for its fruity scent and taste, enhancing the sensory experience of various products.
Used in Pharmaceutical Production:
ETHYL 3-(2-METHYL-1H-IMIDAZOL-1-YL)PROPANOATE serves as a chemical intermediate in the synthesis of pharmaceuticals, contributing to the development of new medications.
Used in Organic Synthesis:
As a chemical intermediate, ETHYL 3-(2-METHYL-1H-IMIDAZOL-1-YL)PROPANOATE is utilized in organic synthesis for the creation of various organic compounds.
Used in Agriculture:
ETHYL 3-(2-METHYL-1H-IMIDAZOL-1-YL)PROPANOATE is used in the formulation of insecticides and fungicides due to its insecticidal and antimicrobial properties, helping to protect crops and enhance agricultural yields.
Used as a Solvent:
In various industries, ETHYL 3-(2-METHYL-1H-IMIDAZOL-1-YL)PROPANOATE functions as a solvent, facilitating processes that require the dissolution of other substances.
ETHYL 3-(2-METHYL-1H-IMIDAZOL-1-YL)PROPANOATE is recognized for its low toxicity and minimal environmental impact, making it a preferred choice in many applications. However, adherence to proper handling and storage protocols is essential for safe usage.

Upstream product

• 693-98-1 2-methylimidazole 
• 140-88-5 ethyl acrylate 
• 539-74-2 Ethyl 3-bromopropionate 

Downstream Products

• 24647-62-9 3-(2-methyl-1H-imidazol-1-yl)propanoic acid 

Relevant academic research and scientific papers

Efficient protocol for Aza-Michael addition of N-heterocycles to α,β-unsaturated compound using [Ch]OH and [n-butyl urotropinium]OH as basic ionic liquids in aqueous/solvent free conditions

The present work emphasizes on a green methodology using designed and synthesized basic ionic liquid, [n-butyl Urotropinium]OH, and commercially available aqueous solution of choline hydroxide [Ch]OH as catalysts for executing Aza-Michael addition of N-heterocycles to α,β-unsaturated compounds at room temperature. The highlighting features of these catalysts include using low concentration of both catalysts along with [Ch]OH being low cost and biodegradable, [n-butyl Urotropinium]OH significantly enhancing the high substrate/catalyst ratio to obtain the desired products in high yield and purity in most cases. Further, both catalysts were recyclable and recoverable up to five cycles.

Intramolecular cyclization of alkylimidazoles

1,2-Dialkylimidazoles can be converted to nucleophilic 2-alkylidene imidazolines upon treatment with (BOC)2O under mild conditions. Incorporation of a β-keto amide carbonyl electrophile in the 2-alkylimidazole side chain results in intramolecul

Polystyrene-supported CuI-imidazole complex catalyst for aza-Michael reaction of imidazoles with α,β-unsaturated compounds

The polystyrene-supported CuI-imidazole complex catalyst was prepared and characterized by IR spectroscopy, elemental analysis, SEM/TEM and TG/DSC. The complex catalyst was globular with the size of 400-500 nm and showed a good thermal stability at high temperature. The immobilized Cu metal in the complex catalyst was about 0.85 mmol/g. By using the catalyst, aza-Michael reaction of imidazoles to α,β-unsaturated compounds was performed with good yields in 4-8 h. The catalyst showed an excellent recycling efficiency over five cycles without distinct leaching of metal from the polymer support.

Synthesis and biological evaluation of novel 99mtc-labelled bisphosphonates as superior bone imaging agents

A series of novel zoledronic acid (ZL) derivatives 1-hydroxy-3-(2-methyl- 1H-imidazol-1-yl)propane-1,1-diyldiphosphonic acid (MIPrDP), 1-hydroxy-4-(2-methyl-1H-imidazol-1-yl)butane-1,1-diyldiphosphonic acid (MIBDP), and 1-hydroxy-5-(2-methyl-1H-imidazol-1-yl)pentane-1,1-diyldiphosphonic acid (MIPeDP) were prepared and successfully labeled with 99mTc in high labeling yields. The in vitro stability and in vivo biodistribution of 99mTc-MIPrDP, 99mTc-MIBDP and 99mTc-MIPeDP were investigated and compared. The biodistribution studies indicate that the radiotracer 99mTc-MIPrDP has highly selective uptake in the skeletal system and rapid clearance from soft tissues. The present findings indicate that 99mTc-MIPrDP holds great potential for use in bone imaging.

NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF

Disclosed are novel imidazolylalkylcarbonyl derivatives useful as calcium channel modulators and a preparation method of the same. Also disclosed is a method for the treatment of diseases by administering the above compounds based on their inhibitory acti

Novel Tetrahydropyridothiophenes

Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.