2465-93-2

Basic information

• Product Name: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE
• Synonyms: 3,3',3''-[1,2,3-Propanetriyltris(oxy)]tris(propanenitrile);1,2,3-Tris(2-cyanoethoxy)propane,85%,tech.;3,3’,3’’-[1,2,3-propanetriyltris(oxy)]tris-propanenitril;TIMTEC-BB SBB007767;GLYCEROL TRIS(2-CYANOETHYL) ETHER;3,3',3''-(1,2,3-PROPANETRIYLTRIOXY)TRIPROPIONITRILE;3,3',3''-(GLYCERYLTRIOXY)TRIPROPIONITRILE;1,2,3-TRIS(2-CYANOETHOXY)PROPANE
• CAS NO: 2465-93-2
• Molecular Formula: C₁₂H₁₇N₃O₃
• Molecular Weight: 251.28
• EINECS: 219-573-5
• Product Categories: Dinitriles & Trinitriles;Trinitriles;Gas Chromatography;Packed GC;Stationary Phases
• Mol File: 2465-93-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 394.44°C (rough estimate)
• Flash Point: >93.33 °C
• Appearance: /Liquid
• Density: 1.11
• Refractive Index: 1.4600 to 1.4640
• Water Solubility: Soluble in water.
• CAS DataBase Reference: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE(2465-93-2)
• EPA Substance Registry System: 1,2,3-TRIS(2-CYANOETHOXY)PROPANE(2465-93-2)

Safety Data

• Safety Statements: 24/25
• RIDADR: UN3276
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 2465-93-2(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless viscous liquid

Uses

1,2,3-Tris(2-cyanoethoxy)propane could be used as the stationary phase in gas-liquid chromatography.

Upstream product

• 124-41-4 sodium methylate 
• 107-13-1 acrylonitrile 
• 56-81-5 glycerol 

Relevant articles and documents

Free-solvent Michael addition of glycerol to acrylic compounds

In this paper, we report the study of the free-solvent nucleophilic addition of alcohols and glycerol to acrylic compounds, in the presence of catalytic bases. With acrylates, Michael addition and transesterification are in competition: only the PTC reaction with t-butyl acrylate gave trifunctionalized glycerol. With acrylonitrile, the cyanoethylation of glycerol varies with catalysts, temperature, time of reactions and amounts of acrylonitrile. Mono functionalisation of glycerol can be obtained in 28% yield. The optimization of the free-solvent Michael addition of glycerol to acrylonitrile (3.4 equiv., 4 mol% NaOH, 5 h) leads to TCEG (tricyanoethylglycerol, 88% yield, 99% purity) without HCl neutralisation, chlorinated solvents or purification (chromatography or distillation). TCEG can be used as a prochiral core of G0.5 dendrimers.