24652-82-2Relevant academic research and scientific papers
One-pot solvent-free reductive amination with a solid ammonium carbamate salt from CO2 and amine
Kang, Philjun,Lee, Kyu Myung,Lee, Won Koo,Lee, Kyu Hyung,Lee, Byeongno,Cho, Jaeheung,Hur, Nam Hwi
, p. 46203 - 46207 (2015/02/19)
Many amines are liquid and their handling is inconvenient compared with the corresponding solids. We transformed a liquid (S)-(-)-1-phenylethylamine 1 to the corresponding neutral solid form 2 by reacting with carbon dioxide. We performed reductive aminat
Efficient, selective, and green: Catalyst tuning for highly enatioselective reactions of ethylene
Smith, Craig R.,Rajanbabu
supporting information; experimental part, p. 1657 - 1659 (2009/04/10)
Fine tuning of the biaryl and amino moieties of Feringa's phosphoramidite ligands yields structurally simpler, yet more efficient and selective, ligands for asymmetric hydrovinylation of vinylarenes and acylic 1,3-dienes. The enantioselectivities and yields observed in the formation of the 3-arylbutenes are among the highest for all asymmetric catalytic processes reported to date for the synthesis of intermediates for the widely used antiinflammatory 2-arylpropionic acids including naproxen, ibuprofen, fenoprofen, and flurbiprofen.
Synthesis and dynamics of atropisomeric (S)-N-(α-phenylethyl)benzamides
Huelgas, Gabriela,Bernès, Sylvain,Sánchez, Mario,Quintero, Leticia,Juaristi, Eusebio,Anaya de Parrodi, Cecilia,Walsh, Patrick J.
, p. 12655 - 12664 (2008/03/17)
The synthesis of atropisomeric 2-substituted benzamides 2a-e, 3a-e, and 4a-e, and characterization by X-ray structure analysis of 2d, 2e, 3c, 3e, 4c, and 4e are reported. Dynamic 1H NMR spectroscopic studies of benzamides 2b-d, 3b-d, and 4b-d i
Optical resolution of DL-3-acylthio-2-methylpropanoic acid
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, (2008/06/13)
An optically active amine compound and a method for preparing same are provided which compound has the structure STR1 in the form of its R-(+) enantiomer or S-(-) enantiomer, wherein R and R1 are independently H, lower alkyl or halogen, R2 is H or lower alkyl and R3 is lower alkyl, the optically active amine is useful in the optical resolution of DL-3-acylthio-2-methylpropanoic acid wherein acyl is acetyl or benzoyl. The optically active D-(+)-3-acylthio-2-methylpropanoic acids are used as intermediated for preparing antihypertensive agents, such as captopril.
