246539-87-7Relevant academic research and scientific papers
Small peptides containing phosphotyrosine and adjacent αMe- phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain
Liu, Wang-Qing,Vidal, Michel,Gresh, Nohad,Roques, Bernard P.,Garbay, Christiane
, p. 3737 - 3741 (1999)
A series of small peptides with the sequence mAZ-pTyr-Xaa-Asn-NH2, where Xaa denotes α-methylphosphotyrosine or its carboxylic mimetics, were synthesized as inhibitors of the Grb2 SH2 domain. Peptide 3 with (α-Me)pTyr as Xaa has the highest aff
