246542-48-3

Upstream product

• 767-00-0 4-cyanophenol 
• 89446-52-6 7-bromo-2-chloro-4-methyl-quinoline 

Downstream Products

• 653592-13-3 (E)-3-[2-(4-Cyano-phenoxy)-4-methyl-quinolin-7-yl]-but-2-enoic acid ethyl ester 
• 246542-89-2 4-[(7-allyl-4-methyl-quinolin-2-yl)-oxy]-benzonitrile 
• 246542-49-4 4-(4-methyl-7-p-tolyl-quinolin-2-yloxy)-benzonitrile 
• 653592-08-6 4-(4-methyl-7-o-tolyl-quinolin-2-yloxy)-benzonitrile 

Relevant academic research and scientific papers

Heterocyclic thrombin inhibitors. Part 1: Design and synthesis of amidino-phenoxy quinoline derivatives

Amidino-phenoxy quinoline derivatives represent a new class of potent thrombin inhibitors with good selectivity and remarkably low molecular weight (MW: 335-391). X-ray analyses of thrombin-bound inhibitors revealed that enzyme inhibition is mainly based on hydrophobic interactions.