246542-89-2

Upstream product

• 24850-33-7 allyltributylstanane 
• 246542-48-3 4-(7-bromo-4-methyl-quinolin-2-yloxy)-benzonitrile 
• 89446-52-6 7-bromo-2-chloro-4-methyl-quinoline 
• 767-00-0 4-cyanophenol 

Downstream Products

• 653592-20-2 [2-(4-cyano-phenoxy)-4-methyl-quinolin-7-yl]-acetic acid 

Relevant academic research and scientific papers

Heterocyclic thrombin inhibitors. Part 1: Design and synthesis of amidino-phenoxy quinoline derivatives

Amidino-phenoxy quinoline derivatives represent a new class of potent thrombin inhibitors with good selectivity and remarkably low molecular weight (MW: 335-391). X-ray analyses of thrombin-bound inhibitors revealed that enzyme inhibition is mainly based on hydrophobic interactions.

Antithrombotic quinoxazolines

Quinoxazolines having antithrombotic activity. Exemplary of those disclosed are: 4-{[6-(N-carboxymethyl-quinolin-8-yl-sulphonylamino)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl]-methyl}-benzamidine, 4-{[6-(1-(N-cyclopentyl-carboxymethylcarbonylamino)-cyclo-propyl)-1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl]-methyl}-benzamidine, and 4-{[7-(N-carboxymethylaminocarbonyl-ethylamino)-4-methyl-quinolin-2-yl]-oxo}-benzamidine.