2466-73-1

Basic information

• Product Name: isobutyl dihydrogen phosphate
• Synonyms: isobutyl dihydrogen phosphate;Phosphoric acid, mono(2-methylpropyl) ester;Phosphoric acid dihydrogen 2-methylpropyl ester
• CAS NO: 2466-73-1
• Molecular Formula: C₄H₁₁O₄P
• Molecular Weight: 154.101501
• EINECS: 219-576-1
• Mol File: 2466-73-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 263.3°Cat760mmHg
• Flash Point: 113°C
• Appearance: /
• Density: 1.279g/cm³
• Vapor Pressure: 0.00305mmHg at 25°C
• Refractive Index: 1.447
• PKA: 2.01±0.10(Predicted)
• CAS DataBase Reference: isobutyl dihydrogen phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: isobutyl dihydrogen phosphate(2466-73-1)
• EPA Substance Registry System: isobutyl dihydrogen phosphate(2466-73-1)

Safety Data

• Hazardous Substances Data: 2466-73-1(Hazardous Substances Data)

Usage

General Description

Isobutyl dihydrogen phosphate is a chemical compound that belongs to the class of organophosphates. It is a colorless liquid with a faint odor, and it is commonly used as a flame retardant and plasticizer in numerous industrial applications. Isobutyl dihydrogen phosphate is known for its high thermal stability and ability to inhibit combustion, making it an important ingredient in the production of various materials, including polymers, textiles, and coatings. Additionally, it is also used as a solvent and a corrosion inhibitor in metalworking processes. While isobutyl dihydrogen phosphate is generally considered to have low toxicity, it is important to handle and store it with care to avoid any potential hazards.

InChI:InChI=1/C4H11O4P/c1-4(2)3-8-9(5,6)7/h4H,3H2,1-2H3,(H2,5,6,7)

Upstream product

• 108229-12-5 di-sec-butyl isobutyl phosphate 
• 126-71-6 triisobutyl phosphate 
• 78-83-1 2-methyl-propan-1-ol 
• 38299-60-4 2-methylpropyl diphenylphosphate 
• 513-38-2 Isobutyl iodide 

Relevant articles and documents

Method for preparing monoalkyl hypophosphite

The invention relates to a method for preparing monoalkyl hypophosphite. The method comprises the steps of oxidizing monoalkyl hydrogen phosphide halate solution by virtue of hydrogen peroxide, wherein the molar ratio of the monoalkyl hydrogen phosphide halate solution to hydrogen peroxide is 1 to 2 or 1 to 2.1, and the reaction temperature is between (-50)-(20) DEG C. The molecular formula of monoalkyl hypophosphite is RP(H)OOH, wherein R is C1-C10 straight-chain, branched-chain alkyl groups. The method for preparing monoalkyl hypophosphite has the beneficial effects that the reaction yield is more than 80%, and water and halogen hydride can be easily evaporated at a reduced pressure after the reaction is finished and can be recycled by virtue of a sodium hydroxide solution and are not the main content of the invention, so that the method described by the invention is safe, environment-friendly and economic.

Determination of phosphoric acid mono- and diesters in municipal wastewater by solid-phase extraction and ion-pair liquid chromatography-tandem mass spectrometry

The first analytical method for the determination of 13 phosphoric acid mono- and diesters from aqueous samples is presented. The method consists of solid-phase extraction (SPE) and ion-pair liquid chromatographic separation with tri-n-butylamine coupled to electrospray ionization tandem mass spectrometry in the negative ion mode. Due to a lack of pure standards, only 3 of the 13 esters could be quantified. SPE recoveries ranged from 71 to 112% for di-n-butyl phosphate, diphenyl phosphate, and di-(2-ethylhexyl) phosphate (DEHP) with limits of quantification from 7 to 14 ng/L for 100-mL samples. At analyte concentrations ≥1 μg/L, aqueous samples can be analyzed by direct injection without extraction. In municipal wastewater, six diesters and one monoester were unambiguously identified by comparison with synthesized reference material. DEHP showed highest concentrations of 60 and 5 μg/L in raw and treated wastewater, respectively. The detection of monoethylhexyl phosphate was confirmed by LC-Q-TOF-MS analysis, and it was found at a concentration level comparable to DEHP. Laboratory degradation tests show that phosphoric acid diesters can be formed as intermediates in the microbial degradation of trialkyl phosphates that are being used as flame retardants and plasticizers.

CONVENIENT SYNTHETIC ROUTE TO MONO- OR DIAKLYL PHOSPHATE FROM INORGANIC PHOSPHORUS ACIDS

Mono- or dialkyl phosphate was synthesized in a favorable yield by oxidation of phosphonic or phosphinic acid in alcohol with oxygen at the presence of a catalytic amount of copper(II)chloride.The reaction may proceed via the formation of corresponding phosphorochloridate or phosphorochloridite.